The OncoAlert Weekly Round Up April 17-24, 2025

The OncoAlertWeekly Round Up   
Covering the TOP of the week April 18-24, 2025 

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Discussing:
UPDATE on DESTINY-Breast09
https://astrazeneca.com/media-centre/press-releases/2025/enhertu-combination-improved-pfs-in-1l-her-positive-mbc.html

UPDATE on ASCENT 04
https://gilead.com/news/news-details/2025/trodelvy-plus-keytruda-demonstrates-a-statistically-significant-and-clinically-meaningful-improvement-in-progression-free-survival-in-patients-with-previously-untreated-pd-l1-metastatic-trip

Annual Report to the Nationon the Status of Cancer, featuring state-level statistics after the onset of the COVID-19 pandemic
https://acsjournals.onlinelibrary.wiley.com/doi/full/10.1002/cncr.35833

Osimertinib vs. Afatinib in 1L therapy of atypical EGFR-mutated metastatic non-small cell lung cancer
https://lungcancerjournal.info/article/S0169-5002(25)00443-X/fulltext

Targeting Lung Cancer with Precision: The ADC Therapeutic Revolution
https://link.springer.com/article/10.1007/s11912-025-01655-5

Prevalence by therapy line and incidence of breast cancer brain metastases in 18 075 patients
https://academic.oup.com/jnci/advance-article-abstract/doi/10.1093/jnci/djaf048/8101485?login=false

European screening platform for EORTC clinical trials in advanced colorectal cancer ‘SPECTAcolor’
https://esmogastro.org/article/S2949-8198(25)00037-8/fulltext

Korea, Japan, Europe, and the United States: Why are guidelines for gastric cancer different?
https://link.springer.com/article/10.1007/s10120-025-01613-x

Outpatient Administration of Chimeric Antigen Receptor T-Cell Therapy Using Remote Patient Monitoring
https://ascopubs.org/doi/10.1200/OP-25-00062

Safety and Activity of Fibroblast Growth Factor Receptor Inhibitors in Advanced Malignancies
https://ascopubs.org/doi/10.1200/PO-24-00896?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed