Bianca Brandon is joined by Professor Marcus Schultz and Dr Prashant Nasa to discuss their recent Position Paper reporting insights from an international Delphi expert panel on defining and subphenotyping ARDS. The findings underscore the need to refine the ARDS definition to better address heterogeneity of the condition and improve diagnostic precision, with use of subphenotyping where appropriate.

Read the full article:

https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00115-8/fulltext?dgcid=buzzsprout_icw_podcast_Jun_25_lanres

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Bianca Brandon, Senior Editor at The Lancet Respiratory Medicine, is joined by Professor Hjalmar Bouma to discuss a new review on sepsis in immunocompromised patients, exploring the diagnostic challenges, complexities of immune status, and future directions for targeted therapies. The episode also analyses the increased vulnerability of specific patient groups, the importance of biomarker-driven personalised medicine, and the need for improved representation of immunosuppressed patients in clinical trials. 

Read the full article:

https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00124-9/fulltext?dgcid=buzzsprout_icw_podcast_May_25_lanres

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Deputy Editor of The Lancet Respiratory Medicine Ari Colosio discusses the critical findings of a new epidemiological study on pulmonary embolism in children and adolescents with Simon Wolf from the University Hospital of Zurich. 

This episode delves into the prevalence, risk factors, and clinical implications of this rare but serious condition, highlighting the need for increased awareness and further research.

Read the full article:

https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(24)00412-0/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanres

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Dr Sandeep Sahay and Professor Franck Rahaghi discuss their Personal View on future treatment paradigms in pulmonary arterial hypertension.

Read the full paper, Future treatment paradigms in pulmonary arterial hypertension: a personal view from physicians, health authorities, and patients, here: https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(24)00425-9/fulltext

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Il Professor Sergio Harari commenta i risultati di un trial clinico di fase 2 volto a valutare l’attivita’ e la sicurezza del farmaco nintedanib come trattamento in pazienti affetti da linfangioleiomiomatosi (LAM).

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Professor Sergio Harari joins us to discuss the results of a phase 2 clinical trial evaluating activity and safety of nintedanib in people with lymphangioleiomyomatosis (LAM).

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Dr Robert Kullberg joins us to discuss his Viewpoint on empiric antibiotic therapy for sepsis and the importance of reducing unnecessary use of anti-anaerobic antibiotics.

Read the full article:
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(24)00257-1/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanres

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Professor Heather Zar joins The Lancet Respiratory Medicine to discuss early-life RSV disease and long-term respiratory health. This topic will be covered in one of four Series papers in a cross-journal Series with The Lancet.

You can read the Series of papers at:
https://www.thelancet.com/series/respiratory-syncytial-virus?dgcid=buzzsprout_icw_podcast_generic

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Dr Margaux Mesle discusses estimates of lives directly saved by COVID-19 vaccination programs in the WHO European Region in the period from 2020 to 2023 and public health implications.

Read the full article:
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(24)00179-6?dgcid=buzzsprout_icw_podcast_generic_lanres

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Professor James Hull joins us to discuss his recent Spotlight on protecting the respiratory health of athletes ahead of the Summer Olympics and Paralympics.

Read the full article:
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(24)00183-8?dgcid=buzzsprout_icw_podcast_generic_lanres

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Professor Eric Lim discusses the outcomes after extended pleurectomy decortication plus chemotherapy versus chemotherapy alone for pleural mesothelioma.

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Dr Anne Chang discusses the burden of chronic respiratory diseases in Indigenous people.

Read the full article:
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(24)00008-0/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanres

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Professor Daniel Steinfort and Professor Shankar Siva discuss the effect of systematic endoscopic mediastinal staging on radiotherapy field planning in patients with locally advanced non-small-cell lung cancer.

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Prof Daniel Prieto-Alhambra, Dr Annika Jödicke, and Dr Martí Català discuss the effectiveness of COVID-19 vaccines to prevent Long COVID, estimated to affect up to 20% of those infected with SARS-CoV-2.

Read the full article:
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(23)00414-9/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanres

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Dr Tim Nicholson and Dr Sarah Gorst discuss the development of an international Delphi consensus study on a core outcome measurement set for long COVID and how it will be used to inform future research and clinical care.

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Dr Betty Raman discusses multiorgan MRI findings in patients after hospitalisation with COVID-19.

Read the full article:
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(23)00262-X/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanres

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Dr Keith Chappell discusses the bivalent recombinant vaccine for COVID-19 following the study by Dayan and colleagues, with focus on vaccine access, variants and boosters, tolerability and side effects, as well as hopes for future trials.

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Prof. James Chalmers discusses the characteristics of patients with bronchiectasis across Europe, the differences between countries, and possible differences in clinical outcomes, based on data from the EMBARC registry.

Read the full article:
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(23)00093-0/fulltext?dgcid=buzzsprout_tlv_episode-notes_general_general

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Prof Richard Costello discusses the use of digital measurements of medication adherence and lung function to guide management of uncontrolled asthma.

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Dr Keiju Aokage discusses segmentectomy for ground-glass-dominant lung cancer with a tumour diameter of 3 cm or less.

Read the full article:
Segmentectomy for ground-glass-dominant lung cancer with a tumour diameter of 3 cm or less including ground-glass opacity (JCOG1211): a multicentre, single-arm, confirmatory, phase 3 trial

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Carol Hodgson discusses recent advances in our understanding of in-hospital and post-discharge outcomes in critically ill patients who receive ECMO.

Read the full article:
Comparative outcomes of extracorporeal membrane oxygenation for COVID-19 delivered in experienced European centres during successive SARS-CoV-2 variant outbreaks (ECMO-SURGES)

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Emma Grainger, Editor-in-Chief of The Lancet Respiratory Medicine, discusses the January issue and plans to celebrate the 10-year anniversary of the journal.

Read the Editorial from the 10th anniversary issue:
Past learnings and new beginnings in the digital age

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Vivienne Kahlmann and Catharina Moor discuss a study looking at online mindfulness-based cognitive behaviour treatment to address fatigue associated with sarcoidosis.

Read the full article:
Online mindfulness-based cognitive therapy for fatigue in patients with sarcoidosis (TIRED)

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Yves Lacasse joins The Lancet Respiratory Medicine to discuss a meta-analysis on the effectiveness of home oxygen use for patients with COPD.

Read the full article:
Home oxygen for moderate hypoxaemia in chronic obstructive pulmonary disease: a systematic review and meta-analysis

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Rachael Evans discusses the needs of people with long COVID and the latest findings from the PHOSP-COVID study.

Read the full article:
Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID)

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