The Sports Docs Podcast

161: Overtime – Platelet Concentration Explains PRP Outcomes in Lateral Epicondylitis

Welcome to Overtime with the Sports Docs. On each of these mini episodes, we chat about a new article or new surgical technique in the field of sports medicine. We’ll give you our quick take on the most recent data and how
this data will impact our practice.

Today, we’re talking about one of the hottest topics in sports medicine — platelet rich plasma for lateral epicondylitis. If you’ve ever wondered why PRP seems to work great for some patients… and not at all for others — this paper gives us a compelling answer.


We’re reviewing an article from the January 2025 issue of AJSM titled “Platelet Concentration Explains Variability in Outcomes of Platelet-Rich Plasma for Lateral Epicondylitis.” The key takeaway from the systematic review and meta-analysis is that PRP isn’t one standard treatment. The dose matters and platelet concentration may explain most of the conflicting data we’ve seen over the years.