One of the most important things a healthy brain needs is appropriate neurotransmitter activity. Neurotransmitters regulate our brain function, our energy, our focus, our mood, and our lives. Imbalances in neurotransmitters can come from many things, including past trauma, unhealthy relationships, bad habits, chronic stress, poor gut health, crappy diet, toxins, autoimmunity, neuroinflammation....the list goes on and on, but it can be helpful to know which neurotranmitters are imbalanced in the hopes of supporting your specific brain functions and symptoms. The most important neurotransmitters, which I discuss in this podcast, are:
Serotonin - regulates some aspects of mood, appetite, happiness, enjoyment of activities, appreciation of art.
Acetylcholine - regulates working memory, computation, muscle contractions, and parasympathetic nervous system (vagus nerve) activity to the gut.
Dopamine - important for motivation, pleasure, focus, mood, addiction, thrill-seeking.
Epinephrine/Norepinephrine - aka "adrenaline", stimulates "fight or flight" stress response centrally in the brain and also peripherally from the adrenal glands.
GABA - the primary "calming" neurotransmitter, GABA is inhibitory and is often inadequate in symptoms of anxiety, depression, and neuroexcitation.
These neurotransmitters can all be modulated with lifestyle strategies and targeted nutraceuticals, whether it be providing the building blocks for the neurotransmitters itself (tyrosine for dopamine for example), or impacting the receptor sensitivity (L-theanine for GABA), or using nutrients to support certain pathways like the Kynurenine Pathway, Dopamine Beta Hydroxylase, or other genetic pathways (COMT, MTHFR, MAO) of neurotransmitter metabolism. Supporting neurotransmitter metabolism can be a game changer when supporting brain function, and my goal is to teach people how to solve their own puzzles, so I hope this is helpful, next episode is part 3/4, brain regions!