The Hematology Podcast

Vaccinations after Hematopoietic Stem Cell Transplant

Mats Merup/Sigrun Einarsdottir Season 5 Episode 25

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Hematopoietic stem cell transplantation is a crucial part of the treatment of many hematological malignancies. One important effect is alteration of the immune system. To overcome this, vaccinations after hematopoietic stem cell transplantation are a vital part of post-transplant care. The timing, and effectiveness of vaccines in this setting remain complex, as immune reconstitution varies widely. In this episode, we will explore current strategies and emerging insights into how best to safeguard allogenic transplanted patients against infections.

Our guest is Sigrun Einarsdottir, hematologist and researcher with a focus on immune responses in immunocompromised patients. She completed her hematology fellowship and PhD at Sahlgrenska University Hospital in Gothenburg, Sweden in 2022, with her thesis centered on vaccine responses post-transplant. Sigrun is now a postdoctoral fellow at Memorial Sloan Kettering Cancer Center, she continues her work on infections and vaccine responses, particularly after CAR T-cell therapy. Today, she’ll share her expertise on optimizing vaccination strategies in this vulnerable group.


MAT-BE-2501090 (ver.1) 09 2025