HER2+ Horizons: Debates and Decisions in Metastatic Breast Cancer: Episode 1

First-Line Therapy—Has the Standard of Care Shifted for Good?

In this episode, Dr. Sara Tolaney, of Dana-Farber Cancer Institute, discusses how DESTINY-Breast09 is redefining first-line treatment in HER2-positive metastatic breast cancer. She explores whether T-DXd plus pertuzumab should replace the long-standing THP regimen, the future role of induction-maintenance strategies, and open questions on optimal therapy duration.  

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