Use of diabetes medications in non-approved (aka off-label) ways is increasingly common. This month, Amy and Liz dig into common off-label usage of Type 2 medications in insulin-deficient diabetes. Meds like GLP-1s, SLGT2’s, and metformin have an established history as a treatment for improving insulin sensitivity in T1’s. Ever wonder how that works and what the potential down sides are? While they’re on the topic of medications used for non-FDA-approved purposes, stay for the second half of the episode where they delve into use of supplements (cinnamon and turmeric) for diabetes management and if/how it works (the answer may surprise you) (or not).
Instagram @diacastpodcast (https://www.instagram.com/diacastpodcast/)
Facebook Diacast (https://www.facebook.com/diacastpodcast)
Email us at contact@diacast.com
Please feel free to join the wonderful diabetes communities on Reddit and Discord.
r/diabetes subreddit:
https://www.reddit.com/r/diabetes/
r/Diabetes discord:
Patreon (help us stop losing money - plus early access, bloopers, and more!)
Reference Links
https://diatribe.org/how-people-diabetes-are-getting-during-ozempic-shortage
Off-Label Medication in T1D https://www.utsouthwestern.edu/newsroom/articles/year-2023/february-type-1-diabetes.html
Current and Therapeutic Use of Metformin https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915435/
Metformin in T1D [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771191/#:~:text=Metformin reduces hepatic glucose production,20%2C 21%2C 26]](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771191/#:~:text=Metformin reduces hepatic glucose production,20%2C 21%2C 26])
https://www.sciencedirect.com/science/article/pii/S2589936821000049
Metformin as an anti-cancer med https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497052/#:~:text=Based on recent analyses and,prostate%2C colon%2C pancreas%2C and
TZDs in Diabetic Children and Beta Cell Preservation https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890222/
Use of diabetes medications in non-approved (aka off-label) ways is increasingly common. This month, Amy and Liz dig into common off-label usage of Type 2 medications in insulin-deficient diabetes. Meds like GLP-1s, SLGT2’s, and metformin have an established history as a treatment for improving insulin sensitivity in T1’s. Ever wonder how that works and what the potential down sides are? While they’re on the topic of medications used for non-FDA-approved purposes, stay for the second half of the episode where they delve into use of supplements (cinnamon and turmeric) for diabetes management and if/how it works (the answer may surprise you) (or not).
Instagram @diacastpodcast (https://www.instagram.com/diacastpodcast/)
Facebook Diacast (https://www.facebook.com/diacastpodcast)
Email us at contact@diacast.com
Please feel free to join the wonderful diabetes communities on Reddit and Discord.
r/diabetes subreddit:
https://www.reddit.com/r/diabetes/
r/Diabetes discord:
Patreon (help us stop losing money - plus early access, bloopers, and more!)
Reference Links
https://diatribe.org/how-people-diabetes-are-getting-during-ozempic-shortage
Off-Label Medication in T1D https://www.utsouthwestern.edu/newsroom/articles/year-2023/february-type-1-diabetes.html
Current and Therapeutic Use of Metformin https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7915435/
Metformin in T1D [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771191/#:~:text=Metformin reduces hepatic glucose production,20%2C 21%2C 26]](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771191/#:~:text=Metformin reduces hepatic glucose production,20%2C 21%2C 26])
https://www.sciencedirect.com/science/article/pii/S2589936821000049
Metformin as an anti-cancer med https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497052/#:~:text=Based on recent analyses and,prostate%2C colon%2C pancreas%2C and
TZDs in Diabetic Children and Beta Cell Preservation https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3890222/