ID:IOTS - Infectious Disease Insight Of Two Specialists

24. Ambl(er)ing through beta lactamases

Infectious Disease: Insights of Two Specialists Season 1 Episode 24

Join Jame and Callum as they discussion all things beta lactamase including ESBL, AmpC and Carbapenemases.  We talk through classification systems, patterns of resistance and some methods of detection. 

Some resources we found helpful:

Summary of beta lactamase classification:
https://microbeonline.com/betalactamase-classification/

Summary of AmpC:
https://www.idstewardship.com/heck-yes-get-amped-updates-ampc-harboring-bacteria/

EUCAST detection of resistance:
https://www.eucast.org/fileadmin/src/media/PDFs/EUCAST_files/Resistance_mechanisms/EUCAST_detection_of_resistance_mechanisms_170711.pdf

UK SMI on Carbapenemases:
https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1080594/B_60i3.1.pdf

More in depth AmpC:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763639/

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