AppNexus Founder Brian O'Kelley - adtech, AI, advertising and more AI

"World of DaaS"

"World of DaaS"
AppNexus Founder Brian O'Kelley - adtech, AI, advertising and more AI
Apr 29, 2025 Episode 193
Word of DaaS with Auren Hoffman

Brian O'Kelley is the co-founder and former CEO of AppNexus, which built core infrastructure for programmatic advertising and was acquired by AT&T for $1.6 billion in 2018. He's now the co-founder and CEO of Scope3, a company working to reduce the carbon footprint in digital advertising.

In this episode of World of DaaS, Brian and Auren discuss:

  • The zero-sum game of auction paradigms
  • AI tools revolutionizing software development
  • Building personal brands in tech
  • Climate tech's shifting business case


Looking for more tech, data and venture capital intel? Head to worldofdaas.com for our podcast, newsletter and events, and follow us on X @worldofdaas.  

You can find Auren Hoffman on X at @auren and Brian O’Kelley on X at @bokelley

Editing and post-production work for this episode was provided by The Podcast Consultant (https://thepodcastconsultant.com)



Episode Artwork AppNexus Founder Brian O'Kelley - adtech, AI, advertising and more AI 48:30 Episode Artwork Anduril Co-Founder Trae Stephens - Hard Tech & Modern Defense Strategy 50:17 Episode Artwork Fmr Verisk CEO Scott Stephenson - building a $40 billion data company 51:00 Episode Artwork a16z’s Martin Casado - building with AI 49:50 Episode Artwork Mediaocean CEO Bill Wise - building the operating system for advertising 45:47 Episode Artwork Rob Henderson - Luxury Beliefs: How Elites Exploit the Poor 50:53 Episode Artwork Lead Bank CEO Jackie Reses - fintech's regulatory reckoning: who survives, who thrives 47:36 Episode Artwork Hello Patient CEO Alex Cohen - SaaS sprawl and meme culture 57:01 Episode Artwork Mario Gabriele - mullet capitalism & modern media empires 48:53 Episode Artwork Annie Duke - winning bets: decision science in venture capital 53:24 Episode Artwork Insight Partners Deven Parekh - navigating global markets in uncertain times 49:33 Episode Artwork Viant $DSP CEO Tim Vanderhook - ad tech, fraud, and the first-party data revolution 57:08 Episode Artwork PubMatic $PUBM CEO Rajeev Goel - hidden infrastructure of digital advertising 50:09 Episode Artwork Mark Pincus - Product Instincts: “Proven, Better, New” 58:04 Episode Artwork Taboola $TBLA CEO Adam Singolda - AI powered content discovery 43:48 Episode Artwork DoubleVerify $DV CEO Mark Zagorski - the $100B war against digital ad fraud 41:54 Episode Artwork Sayari CEO Farley Mesko - mapping global financial crime 40:31 Episode Artwork Magnite $MGNI CEO Michael Barrett - from linear TV to AI 42:48 Episode Artwork Samo Burja - live players vs NPCs: hidden forces shaping history 1:01:45 Episode Artwork Qualia CEO Nate Baker - real estate's digital infrastructure layer 38:31 Episode Artwork Life360 $LIF CEO Chris Hulls - trust, data, and modern parenting 54:21 Episode Artwork Fivetran CEO George Fraser - data for the AI revolution 43:39 Episode Artwork DJ Patil - Data Science pioneer on AI, healthcare, and defense 57:34 Episode Artwork Morning Brew founder Alex Lieberman - what B2B marketers get wrong 52:05 Episode Artwork Altana CEO Evan Smith - Supply Chains, China, and Globalization 2.0 44:27