EP 61: How (And Why) To Think About Computation in Biology with Dr. Corey Maley

The Future Conceived

The Future Conceived
EP 61: How (And Why) To Think About Computation in Biology with Dr. Corey Maley
Jun 28, 2026
SSR Podcast

This season we’ve been exploring the concept of mechanism in reproductive biology. In a recent episode with Dr. Dan Nicholson we learned that scientists have historically framed problems in biology through metaphors that reflect everyday technologies. In fact, the word mechanism implies that biology has machine-like qualities. Today, as digital computers permeate nearly every part of our daily lives, it seems worth examining whether computing metaphors are poised to reshape our understanding of biology in the 21st century, much as the machine metaphor did in the latter half of the 20th century. 

Today I have the pleasure of chatting with Dr. Corey Maley of Purdue University. Corey is a philosopher with a background in neuroscience who studies the fundamental nature of computation… A topic that is much broader than I originally thought. Our chat covers the role of philosophy in science, the definition of computation, and when biological systems are (and are not) literally computers. 

Learn More about SSR at SSR.org

Learn more about Dr. Maley's work at: https://www.cla.purdue.edu/directory/profiles/corey-maley.html

Link to Paper "How (and Why) To Think That The Brain is Literally A Computer".

Episode Artwork EP 61: How (And Why) To Think About Computation in Biology with Dr. Corey Maley 1:22:26 Episode Artwork EP60: How To Think About Biology with Dr. Dan Nicholson 2:10:43 Episode Artwork E59: Janice Bahr Junior Scientist Travel Award with Dr. Camilla Hughes 24:55 Episode Artwork EP 58: Early Embryo Development: The Material Physics of Cell Division with Dr. Colm Kelleher 1:33:44 Episode Artwork EP 57: Interview with RV Short Medal Recipient Dr. David Pepin 38:48 Episode Artwork EP 56: Embryo Development: Metabolism and the Uterine Microenvironment with Dr. Kosta Simintiras 58:19 Episode Artwork EP 55: Alternative Careers in Reproductive Biology: Dr. Jane Fenelon, Marsupial Assisted Reproduction Lead at Colossal Biosciences 24:08 Episode Artwork EP 54: Embryo Development: Genetic Programs with Dr. Ramiro Alberio 1:21:57 Episode Artwork EP 53: 2024 Repro BioArt Awards with Ingrid Carvacho, and Martin Estermann 27:59 Episode Artwork EP 52: Carl G. Hartman Award with Dr. Teresa K. Woodruff 33:14 Episode Artwork EP 51: Egg Activation: Cell Regulatory Systems with Dr. Jim Ferrell 1:17:07 Episode Artwork EP 50: Virendra B. Mahesh New Investigator Award with Dr. Diana Monsivais 21:14 Episode Artwork EP 49: Egg Activation: Calcium Dynamics with Dr. Karl Swann 1:10:56 Episode Artwork EP 48: The Calcium Code—SSR Research Award Interview with Dr. Carmen Williams 50:33 Episode Artwork EP 47: Egg Activation: Molecular Mechanisms with Dr. Mariana Wolfner 1:09:14 Episode Artwork EP 46: Fuller W. Bazer Award with Marcella Pecora Milazzotto 18:23 Episode Artwork EP 45: Sperm Capacitation: Intelligent Motion with Dr. Meisam Zaferani 57:18 Episode Artwork EP 44: Alternative Careers in Reproductive Biology: Dr. Eglė Ortega, Senior Embryologist at Fertility Institute of Hawaii 21:18 Episode Artwork EP 43: Sperm Capacitation: Energy Metabolism with Dr. Melanie Balbach 1:18:28 Episode Artwork EP 42: Sperm Capacitation: Molecular Mechanisms with Dr. Pablo Visconti 1:47:02 Episode Artwork EP 41: 2025 Training Mentoring Award Interview with Marisa Bartolomei 48:14 Episode Artwork EP 40: What's New at BOR? Expanded Scope, Special Issues, and More! 29:52 Episode Artwork EP 39: Interview with 2024 Roger V Short Medal Awardee Dr. Francesca Duncan 42:51 Episode Artwork EP 38: Interview with 2024 SSR Jansen Distinguished Leadership and Service Award Winner Dr. Katherine Loveland 43:54 Episode Artwork EP 37: Interview with 2024 Carl G. Hartman Award Winner Dr. Francesco DeMayo 42:34