The current standard of care is to provide a bolus of 30 mL per kg of isotonic fluid for patients with septic shock. Recent retrospective studies question this practice. Join host, Geoff Wall, as he reviewed a NEJM article on the role of fluids in septic shock.
Large boluses of fluid during septic shock may have unintended adverse events. Some data show that an approach with restrictive fluids may have no difference in death or adverse outcomes.
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00:00 - Introductions
01:38 - Background on Septic Shock and Current Treatment
04:47 - Meyhoff et al Study
15:17 - Gamechanger: Study Findings
22:51 - Connecting to Practice
23:57 - Closing Remarks
Geoff Wall, PharmD, BCPS, FCCP, CGP
Professor of Pharmacy Practice, Drake University
Internal Medicine/Critical Care, UnityPoint Health
References and Resources
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Get a membership & earn CE for GameChangers Podcast episodes (30 mins/episode)
Upon successful completion of this knowledge-based activity, participants should be able to:
1. Critique the Meyhoff et al study evaluating restrictive fluids in septic shock
2. Discuss current approaches to fluid resuscitation in patients with septic shock
0.05 CEU/0.5 Hr
Initial release date: 10/10/2022
Expiration date: 10/10/2023
Additional CPE and CME details can be found here.
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