Alexander Disease Research Update

Alexander Disease Research Update - Episode #10: effects of variants in the rod domain on GFAP assembly and aggregation, new ideas about functions of intermediate filaments

Albee Messing

Albee Messing and Natasha Snider discuss the following recent publication: 

[04:44]       Effects of Alexander disease-associated mutations on the assembly and organization of GFAP intermediate filaments (Molecular Biology of the Cell, in press) 

[28:53]       Questions from email regarding heritability, penetrance, and skipping generations.

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