Alexander Disease Research Update – Episode #26: Changes in gene expression and cognitive function in the rat model

Albee Messing, Tracy Hagemann, and Rob Berman discuss the following recent publication: 

[02:01]       GFAP mutation and astrocyte dysfunction lead to a neurodegenerative profile with impaired synaptic plasticity and cognitive deficits in a rat model of Alexander disease

eNeuro (in press)  [full text]

Send your questions and feedback to:  amessing@wisc.edu

Help support research on Alexander Disease at the University of Wisconsin-Madison's Waisman Center:

          https://alexander-disease.waisman.wisc.edu/donate/

Chapters

• 2:02 GFAP mutation and astrocyte dysfunction lead to a neurodegenerative profile with impaired synaptic plasticity and cognitive deficits in a rat model of Alexander disease