Bioengineering and Coffee

Episode 2

Maggie L Season 1 Episode 2

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0:00 | 26:46

Welcome back to Bioengineering and Coffee! Tune in to hear my interview with Ms. Mallory Evanoff, who is a 5th year pHD student at UCSD. She is part of the Komor Lab, which is a DNA damage repair and genome engineering lab. 

In this episode, Ms. Evanoff teaches us about the basics of CRISPR and its origin from a bacteria immune system. She then addresses the advantages and disadvantages of CRISPR, and any concerns associated with CRISPR such as off-target effects. Afterwards, she dives into her work with base editors, which change one base in the genome (single nucleotide variants or SNVs).