Labetalol

• Trade: Normodyne
• Class: Beta blocker 
• MOA:  Binds with beta1, beta2 and Alpha1 receptors. Inhibits the strength of the hearts contractions, as well as heart rate. This results in decrease in cardiac Oxygen consumption. 
• Indication: ACS, SVT, severe HTN
• Contraindications: Hypotension, Cardiogenic shock, acute pulmonary edema, heart failure, severe bradycardia, Sick sinus syndrome, second or third degree heart block, bronchospasm. 
• Side effects: Usually mild, Hypotensive symptoms, N/V, Bronchospasm, arrhythmia, bradycardia, AV block
• Dosing: 

Adult 

10mg IV/IO Over 1-2mins may repeat every 10 mins to a max dose of 150mg

Pedi 

0.4-1mg/kg per hour to a max dose of 3mg/kg per hour