Paramedic Drug Cards

Hydrocortisone

Michael Egan
  • Trade – Cortef
  • Class – Corticosteroid 
  • MOA – Reduces inflammation by multiple mechanisms. As a steroid it replaces the steroids that are lacking in adrenal insufficiency.
  • Indications – Adrenal insufficiency, allergic reactions, anaphylaxis, asthma, COPD
  • Contraindications – Cushing Syndrome, known sensitivity to benzyl alcohol, Use with caution in diabetes, HTN, CHF, known systemic fungal infection, renal disease, idiopathic thrombocytopenia, psychosis, seizure disorder, GI disease, glaucoma. 
  • Side effects – Leukocytosis, hyperglycemia, increased infection, decreased wound healing, increased rate of death from sepsis.  
  • Dosing 

Anaphylactic shock 

Adult 100-500mg IV,IO, or IM 

Pedi 2-10 mg/kg per day IV,IO, or IM max 500mg