Paramedic Drug Cards

Hydroxocobalamin

Michael Egan
  • Trade – Cyanokit
  • MOA:  Antidote, cyanide poisoning adjunct Binds with cyanide to form nontoxic cyanocobalamin, preventing its toxic effects; excreted renally
  • Indications: Treatment of known or suspected cyanide poisioning.
  • Contraindications:  None is the emergency setting
  • Side Effects:  Hypertension, allergic reactions, GI bleeding, nausea, vomiting, dyspepsia, dyspnea, dizziness, headache, injection site reactions.
  • Dosage:  

Adult: 5 g IV infusion over 15 minutes at a rate of 15 mL/min.

Pedi:  70 mg/kg IV one time, may be repeated one time at the same dose.