Diazepam

• Trade: Valium 
• Class: Benzodiazepine
• MOA: Binds to the benzodiazepine receptor and enhances the effects of GABA
• Indications: Anxiety, Skeletal muscle relaxation, anticonvulsant 
• Contraindications: Children younger then 6 months, acute angle glaucoma, CNS depression, alcohol intoxication. 
• Side effects:  Respiratory depression, drowsiness, fatigue, headache, pain at the injection site, confusion, nausea, hypotension, cardiac arrest at high doses
• •Dosing:

Adult: 

Anxiety: 2-10mg IV/IM

Seizure: 5-10mg IV/IO

Pediatric:

Anxiety: 0.2 – 0.3mg/kg IV/IM

Seizure:  Older then 5 years: 1mg IV/IO

Older then 30 days less then 5 years: 0.2 to 0.5mg IV/IO

                Neonate: 0.1-0.3mg/kg IV/IO