Building the Berkshire Hathaway of AI Services | Brennan Pothetes, CEO of Infinity Constellation

Infinite Curiosity Pod with Prateek Joshi

Infinite Curiosity Pod with Prateek Joshi
Building the Berkshire Hathaway of AI Services | Brennan Pothetes, CEO of Infinity Constellation
Jul 16, 2025
Prateek Joshi

Brennan Pothetes is the CEO of Infinity Constellation, an AI-native holding company. They've raised $17M from Freestyle Capital, Charlie Songhurst, and others. 

Brennan's favorite books: Zero to One (Author: Peter Thiel)

(00:01) Lightning Bolt Moment – Origin of Infinity Constellation
(03:48) Transitioning from Founder to Holdco CEO
(07:00) How Infinity Incubates vs Acquires Companies
(09:05) Infinity vs Traditional Venture Studios
(10:58) Aligning Incentives: Founders, Holdco, and Investors
(16:32) Target Markets and How They’re Chosen
(20:27) When a Company Graduates from the Holdco
(23:04) Resource Allocation and “Too Many Toddlers” Problem
(26:29) Shared Infrastructure and the Code Commons
(29:48) Model Choices, Full Stack AI, and the Infinity Playbook
(32:05) First 3 Hires at a Portfolio Company
(33:53) Who is the Real Competition?
(37:03) Infinity’s 5-Year Vision and AI Trends
(38:37) Rapid Fire Round

Episode Artwork Building the Berkshire Hathaway of AI Services | Brennan Pothetes, CEO of Infinity Constellation 47:40 Episode Artwork Agentic Shift in Microservices | Mark Fussell, CEO of Diagrid 34:08 Episode Artwork Building the Android for Robots | Jan Liphardt, founder of OpenMind 46:43 Episode Artwork AI Infra for Long Context Model Training | Anna Patterson, founder of Ceramic AI 39:31 Episode Artwork Building an AI+Data Startup Studio | Tom Chavez, cofounder of super{set} 52:57 Episode Artwork Decentralized Data Foundry for AI | Rowan Stone, CEO of Sapien 38:22 Episode Artwork Converting Cameras into Autonomous AI Agents | Rish Gupta, CEO of Spot AI 38:50 Episode Artwork Are AI Phone Agents Ready for Prime Time? | Alex Levin, CEO of Regal 45:21 Episode Artwork What it Takes to Build a BI Platform | Colin Zima, CEO of Omni 40:07 Episode Artwork Building Billing Infrastructure for AI Companies | Alvaro Morales, CEO of Orb 38:21