The DUTCH Podcast
What Triggers Acne? Optimizing Hormones & Gut Health
Apr 14, 2026
Episode 149
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In this episode, Dr. Jaclyn Smeaton sits down with Dr. Bryant Esquejo, ND to unpack acne through a functional medicine lens, moving far beyond the surface to explore what’s really happening inside the body.
Dr. Esquejo and Dr. Smeaton also discuss:
- Acne as not just a skin condition, but a reflection of imbalances involving hormones, blood sugar, inflammation, and the gut microbiome
- The science behind acne development, from bacterial activity and oil production to deeper drivers like insulin resistance, androgen metabolism, and chronic inflammation
- The influence of diet, stress, sleep, and gut health
- How advanced testing, like hormone metabolite analysis, can reveal hidden imbalances in the body
- Treating acne as an opportunity to better understand and optimize whole-body health
Learn more about Dr. Esquejo and follow him on Instagram @dr.bryant!
Check out Dr. Esquejo’s blog post on blood sugar, insulin, and acne, and read our whitepaper on 5a-Androstanediol as a marker of androgen status in women.
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