Optimizing GLP-1 Outcomes: Starting, Managing & Discontinuing Therapy
The DUTCH Podcast
Chapters
0:54
Episode Introduction
2:48
Journey to Functional Medicine
5:36
Understanding Metabolic Dysfunction in Women
8:42
The Role of Leptin and Insulin Resistance
11:49
GLP-1s: Mechanisms and Patient Considerations
14:56
Women’s Hormonal Status and GLP-1 Response
17:45
Gut Health and Weight Loss Dynamics
20:51
DUTCH Courses: Mastering Functional Hormone Testing
21:36
Cortisol, Stress and Weight Management
28:40
Emerging Research on GLP-1s and Health Benefits
33:54
The Role of GLP-1 in Weight Management
35:38
Exploring New GLP-1 Options
41:45
Potential Beyond Weight Loss: Autoimmune Conditions
43:13
Life After GLP-1: Managing Expectations
49:29
Staying Informed: The Provider's Role
52:38
GLP-1 Research and Additional Resources
The DUTCH Podcast
Optimizing GLP-1 Outcomes: Starting, Managing & Discontinuing Therapy
Jun 23, 2026
Episode 158
DUTCH Test
In this episode, Dr. Bindiya Gandhi joins host Dr. Jaclyn Smeaton to explore GLP-1 receptor agonists through a whole-person, root-cause lens with a particular focus on women’s health.
Their discussion also covers:
- How GLP-1s work, who benefits most, and how to cease therapy successfully
- The role of leptin resistance in weight struggles
- The risk of muscle loss and bone health during GLP-1 therapy
- Using GLP-1s as part of a comprehensive protocol, including optimizing gut health, strength training, and managing cortisol and sex hormones
- Considerations for menopausal women using hormone therapy in addition to GLP-1s
Show Notes
Learn more about Dr. Bindiya Gandhi and follow her on Instagram @drbindiyamd!
Check out our DUTCH Article on GLP-1s and perimenopause.
Become a DUTCH Provider to get access to peer-reviewed and validated research, comprehensive patient reports, and expert clinical support.
