UnabridgedMD
Bringing Hope, driven by science. Isabelle Amigues, MD, is a physician scientist with a speciality in rheumatology. She has trained both in Paris, France as well as Columbia University, in New York City. At age 40, in the midst of an existential crisis, she was diagnosed with stage IV metastatic breast cancer. A timely meeting with a non-traditionally trained practitioner taught her a different approach to disease. She experienced the power of meditation, visualization, energy healing and love. Her journey through cancer inspired her to learn more about these alternative approaches, and now that she has studied many of them she has integrated them into her own practice of medicine. Dr. Amigues is the author of multiple book chapters and scientific articles in rheumatology. She is the founder and CEO of UnabridgedMD.
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UnabridgedMD
From Fatigue to Clarity: Healing Mitochondria and the Brain with Dr. Scott Sherr
In this episode of the UnabridgedMD Podcast, Dr. Isabelle Amigues sits down with Dr. Scott Sherr, board certified internal medicine physician and a pioneer in integrative and functional medicine, to dive deep into the root causes of fatigue, anxiety, and brain fog — and how to begin truly healing the body from the inside out.
They explore the massive role mitochondria play in cellular energy, how chronic stress and sympathetic overdrive disrupt neurotransmitters like GABA and glutamate, and how 94% of Americans are likely living with some level of mitochondrial dysfunction.
Dr. Sherr and Dr. Amigues also discuss the emerging use of methylene blue as a tool to support mitochondrial function — providing a fast-acting bridge to healing while long-term nutritional and lifestyle strategies take effect.
Whether you're a patient experiencing brain fog or fatigue, or a provider seeking deeper root-cause tools, this episode offers actionable insights and science-backed strategies to support mental clarity, emotional balance, and whole-body energy.
Topics Covered:
- The connection between chronic stress, GABA depletion, and anxiety
- How glutamate and GABA work together to balance brain function
- Why 94% of Americans show signs of mitochondrial dysfunction
- The role of nutrients, minerals, and fatty acids in energy production
- How methylene blue supports mitochondrial health and energy
- The sympathetic vs. parasympathetic nervous system and how to reset
- Tools to restore neurotransmitter balance and reduce inflammation
Tune in to learn how to support your brain, restore energy, and shift from survival to healing — with the help of both science and integrative medicine.
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Are you, or someone you love, looking for a rheumatologist near you? Maybe you queried Google for the “best rheumatologist in Denver” and felt that no other arthritis clinic in Denver really seemed personable? Or maybe you are simply looking for a doctor who will listen to you and work with you to achieve disease remission? Well, you have come to the right place. UnabridgedMD has the best rheumatologist in Denver, Colorado and we cannot wait to work with you.