Stretchy Skin, IBS & Knee Pain: The Ehlers-Danlos & Autoimmune Connection

The Autoimmune RESET

The Autoimmune RESET
Stretchy Skin, IBS & Knee Pain: The Ehlers-Danlos & Autoimmune Connection
May 11, 2025 Episode 172
VJ Hamilton

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Could there be a deeper connection between hypermobility, fatigue, and your autoimmune symptoms?

In this episode, I unpack the lesser-known links between Ehlers-Danlos Syndrome (EDS) and autoimmune conditions—exploring why so many people with joint hypermobility also struggle with gut issues, immune reactivity, fatigue, and nervous system dysregulation.

We dive into:

  • Why connective tissue fragility can lead to leaky gut and immune activation
  • The role of mast cell activation, POTS, and vagal nerve dysfunction
  • How your family history (think scoliosis, frequent injuries, clicky joints) may hold important clues
  • Why gluten can be an issue, even without coeliac disease
  • My go-to food, supplement, and lifestyle strategies for supporting this overlap

You’ll also hear practical tips on bone broth, slow-cooked meals, magnesium, vagus nerve support—and how to reframe your diagnosis as a doorway to deeper healing.

Mentioned in this episode:

Whether you’ve been diagnosed with EDS, suspect hypermobility, or simply want to understand your autoimmune body more deeply—this one’s for you.


Thanks for listening! You can join The Autoimmune Forum on Facebook or find me on Instagram @theautoimmunitynutritionist.