Histamine intolerance is a complex and often misunderstood condition that can present with a wide range of symptoms—from digestive issues like abdominal pain and irritable bowel syndrome to allergy-like symptoms such as skin rashes, nasal congestion, runny nose, and headaches.

In this episode of Balance Banter, Kristie Calise breaks down the most common symptoms of histamine intolerance and explains how histamine—an important natural chemical derived from amino acids—plays a key role in the immune system, blood vessels, nervous system, and inflammatory response.

When there is too much histamine in the body or reduced activity of DAO (diamine oxidase), the enzyme responsible for breaking down dietary histamine, symptoms can begin to appear. This can be due to DAO deficiency, enzyme deficiency, gut dysfunction, or increased histamine production within the intestinal mucosa.

You’ll learn about:
• Common symptoms of histamine intolerance and allergy-like reactions
• The role of mast cells, histamine receptors, and the release of histamine
• How DAO enzyme activity impacts histamine levels
• Possible causes including small intestinal bacterial overgrowth, gut infections, and underlying health conditions
• The connection between histamine, the menstrual cycle, and hormonal imbalances
• Why tools like a food diary, elimination diet, or low-histamine diet can be a helpful starting point

Kristie also shares her personal experience navigating severe symptoms, uncovering root causes like mold, infections, and gut dysfunction, and why histamine intolerance should be viewed as a symptom—not the final diagnosis.

If you’re dealing with unexplained health issues, food intolerance, or a wide range of symptoms that don’t seem to make sense, this episode will give you clarity, validation, and a new perspective on your healing journey.

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Disclaimer: The information shared in this podcast is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. This content is not medical advice and should not be used as a substitute for professional medical guidance, diagnosis, or treatment. Always consult with your qualified healthcare provider before making changes to your health, medications, supplements, or lifestyle.