Neuroscience and Beyond
We are young researchers at the forefront of neuroscience in Göttingen, Germany, driven by a passion for discovery and communication. In our monthly conversations, we go beyond publications to discuss the real stories with leading experts: their revolutionary work, their personal paths, the struggles they've overcome, and the big questions driving the field forward.
Our mission is built on a simple, powerful idea: knowledge is the only resource that grows when shared. Through open dialogue, we aim to build a bridge between cutting-edge research and the curious minds eager to understand it.
Supported by the International Max Planck Research School for Neurosciences, the European Neuroscience Institute in Göttingen, the Cluster of Excellence "Multiscale Bioimaging" in Göttingen and SFB1286 Quantitative Synaptology in Göttingen.
This podcast reflects our personal views and is separate from our affiliated institutions.
Neuroscience and Beyond
Decoding memory: plasticity, SUSHI and super-resolution microscopy with Prof. Valentin Nägerl
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In this episode we speak with Prof. Valentin Nägerl, the head of the Synaptic plasticity and super-resolution microscopy group at the Interdisciplinary Institute for Neuroscience and Professor of Neuroscience and Bioimaging at the University of Bordeaux. Together, we delve into the intricacies of memory, demystifying terms like plasticity and synapses. Prof. Nägerl shares his knowledge about what is in between the neurons - the extracellular space. We continue with our recent theme of the super-resolution microscopy and explore another technique called SUSHI. The conversation extends to pressing topics like the reproducibility crisis and issues with the publishing system. Finally, we discuss the future of neuroscience.
Our channel is supported by International Max Planck Research School (IMPRS) for Neurosciences as well as Cluster of Excellence Multiscale Bioimaging (MBExC) in Göttingen, Germany. The views presented on this channel are not representative of IMPRS or MBExC.
Timestamps:
00:00:00 Intro
00:02:30 Early career and motivation for doing science
00:05:43 What makes a research institution world-class?
00:07:32 Establishing own research group in Bordeaux
00:09:08 Research focus: superresolution microscopy, synapses and plasticity
00:13:39 Animal experiments in neuroscience
00:19:43 Diversity of neurons and synapses
00:20:42 Hippocampus, plasticity and memory
00:30:23 STED microscopy and phototoxicity problem in live imaging
00:40:35 Recording neural data from the awake animals
00:42:43 SUSHI - super-resolution shadow imaging
00:46:26 Studying extracellular space
00:56:26 Problems in academia: reproducibility crisis
01:01:30 Problems in academia: publishing system
01:03:13 Work-life balance
01:08:06 Future of neuroscience
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Neuroscience and Beyond team:
Svilen Georgiev
Kristina Jevdokimenko