In this episode, we meet with Susan Stein, a seasoned patient advocate, to discuss the pivotal role of patient advocacy in the realm of clinical trials. We focus on how advocacy influences the development of clinical trial protocols, with an emphasis on minimizing the challenges faced by patients, such as logistical and financial burdens. Key topics include the importance of incorporating patient input in trial planning, particularly in areas like informed consent and the frequency of site visits. Stein highlights the potential of technologies like telehealth to improve patient experiences while retaining critical in-person medical interactions. We also explore the increasing need for diversity in clinical trials and how patient advocacy is adapting to recent shifts in the clinical research industry.