
The Cairn Podcast: Marking the Trail for Veterinarians
A Podcast for Veterinarians and Animal Lovers.
We are your centralized resource for veterinary interests, education, and personal development. How we take care of ourselves, each other, patients and pet parents, and how we grow as members of this community - this is what we hope our podcast provides!
The Cairn Podcast: Marking the Trail for Veterinarians
Rapamycin use in cats with subclinical hypertrophic cardiomyopathy
Join us for this exciting discussion as we welcome Dr. Joshua Stern, DVM, PhD, DACVIM (Cardiology) to discuss results of the recently completed RAPACAT trial, evaluating the effects of delayed release rapamycin on left ventricular wall thickness in cats with hypertrophic cardiomyopathy (HCM). Dr. Stern is the Associate Dean for Research & Graduate Studies and Professor of Cardiology at North Carolina State University School of Veterinary Medicine. He is a global leader in the field of veterinary cardiology genetics, with well over 100 publications to date. Following the success of the RAPACAT trial, Dr. Stern and Trivium Vet are organizing a large multicenter study (the HALT HCM study), for which registration is now open (see link below). We also review the etiology and natural history of HCM in cats, rapamycin's effects on mTOR, additional emerging therapies for treating HCM in cats, and other potential uses of rapamycin in veterinary cardiology.
Episode resources
Delayed-release rapamycin halts progression of left ventricular hypertrophy in subclinical feline hypertrophic cardiomyopathy: results of the RAPACAT trial
The HALT HCM Study information and registration
Trivium Vet