The Mindplex Podcast (Archive)
This is an archive for the original Mindplex Podcast, which wrapped up production in February 2025.
The Mindplex Podcast was hosted by Lisa Rein, Ben Goertzel, Grace Robot and Desdemona Robot. On this show, we pondered AGI, cutting-edge technologies and the evolution of human consciousness. We interviewed a wide variety of interesting thinkers - both human and synthetic - to investigate and better understand the complex topics of our time, so we could learn to shape technologies that will assist us in bringing about a Benevolent Singularity.
Subjects covered included: AGI, the Metaverse, Decentralized Economies, Superlongevity, Superintelligence, Nanotech and Femtotech, Psi, Psychedelics, Experimental Futuristic Art & Music, Robotics, Synthetic Biology, Quantum Computing, Consciousness, Brain-Computer Interfaces, Speculative Physics, Chaos and Complexity and anything else wildly interesting and mind-blowing.
The Mindplex Podcast (Archive)
Episode 20: Michael Lustgarden-Leveraging Biomarkers
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Michael Lustgarden explains how he uses aging biomarkers from a basic CBC panel to track and, with course correction (supplements or diet changes), gradually slow down one's rate of aging.
Michael's basic premise is that aging and disease are biochemical processes that happen over many decades. So if we can track just even the standard biomarkers of organ and systemic function, that's the things you usually get at a yearly physical, even just starting there, if you can track and then knowing how these biomarkers change during aging, and how they relate to all cause mortality risk, or risk of death for all causes, then in theory, you can slow the rate of aging of multiple organ systems down slow your rate of disease and potentially maximize longevity.
Since 2015, Michael has been blood testing up to seven times a year, in order to get a year to year change, to see where his status is. Tracking diet every day, fitness related metrics, cardiovascular system, sleep, the oral microbiome now and epigenetics. He is looking at correlations between the outcome variables with the diet and everything else then, of course, correcting after every test, with the goal of slowing the changes in these biomarkers.
About Dr. Michael Lustgarten:
Dr. Michael Lustgarten is Scientist II on the Nutrition, Exercise Physiology, and Sarcopenia (NEPS) Team at the HNRCA (Human Nutrition Research Center on Aging) at Tufts Medical Center. His current research focuses on the role of the gut microbiome and serum metabolome on muscle mass and function in older adults. He has been a guest lecturer at the Friedman School of Nutrition Science and Policy on topics such as the gut microbiome, serum metabolome, oxidative stress, exercise, and sarcopenia and has contributed to 25 publications in leading peer-reviewed journals that have been cited more than 2,400 times, including 17 manuscripts as the first or last author.
His YouTube channel is here: https://www.youtube.com/channel/UCT1UMLpZ_CrQ_8I431K0b-g
#longevity #aging #biomarkers
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