Precision at the Point of Diagnosis: The Role of Genomic Tests in Personalized Pathology - with Jay Jhaveri

Step into the future of diagnostics with this enlightening episode of PathPulse, the Digital Diagnostic Podcast! Host James Thackeray welcomes Jay Jhaveri, Senior Director at Pacific Edge Cancer Diagnostics, to unravel the profound impact of genomic testing on personalized pathology.

Jay Jhaveri brings a unique blend of extensive clinical background (including general surgery, urology residency, and multiple fellowships) and industry expertise to this discussion. He'll guide you through the pivotal shift from traditional tissue examination to precision pathology, where genomic and transcriptomic signatures revolutionize diagnoses.

In this episode, you'll discover:

• How genomic insights are enabling more accurate risk stratification and truly tailored patient management.
• Concrete examples of how genomic biomarker tests can predict cancer risk, potentially reducing the need for invasive procedures like cystoscopy.
• The transformative role of urine-based genomic tests, specifically the CxBladder test, in diagnosing and monitoring urothelial cancer.
• The significant impact of the recent 2025 AUA Microhematuria Guideline update, which now endorses urinary biomarker testing for intermediate-risk patients.
• The challenges and breakthroughs in adopting these cutting-edge tools in clinical practice, including EMR integration and workflow optimization.

Jay shares compelling real-world data, including a 59% decrease in unnecessary cystoscopies in a study utilizing CxBladder Triage, and discusses how this innovation empowers both clinicians and patients.

Tune in to understand how genomic insights are not just an addition, but a fundamental reshaping of the pathology landscape and patient care. This is a conversation you won't want to miss if you're interested in the leading edge of precision medicine!

View transcript here: https://lumeadigital.com/genomic-test-role-digital-pathology-podcast/

Submit questions for our future recordings here: https://lumeadigital.com/ask-a-pathologist-podcast/

Sponsored by the Digital Diagnostic Summit and Lumea.