The Diagnostic Minute

Synopsis: Ovarian leydig cell tumor (0:01:55)

EssentialPathology, NNMI

Feature Summary of Ovarian leydig cell tumor:

  •  Well circumscribe solid nodule near ovarian hylum 
  • Fusion of cytoplasm to form nuclear-free zones is a key feature 
  • Cytoplasmic Reinke crystals and lipochrome pigments 
  • Fibrinoid material in blood vessels 
  • Typically positive for inhibin, calretinin, and mellan-A