The Nutrition Content Creator Podcast

63: GLP-1s in Practice: Your Top Questions Answered

Episode 63

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0:00 | 28:10

Hundreds of questions came in during our live GLP-1 Journey webinar with Dr. Holly Lucille, ND, RN, Senior Medical Advisor at Fullscript. Today's episode covers the five themes that kept coming up from practitioners in the field.

Note: This content was curated with support from the Fullscript medical advisory team. It is educational, not medical advice. Individual patient decisions around dosing, titration, and medication management belong between your patient and their prescribing physician.

In This Episode:

Protein and Muscle Preservation — Why 1.2 to 1.6 g/kg is your floor, not your target. Adjusted body weight calculations, the protective triad for lean mass, and creatine as a practitioner-recommended add-on.

Managing GI Side Effects — Why low-dose side effects still happen, the low-and-slow framework, cooked vs. raw vegetables, SIBO risk, and supplement support including SunFiber, digestive enzymes, and TUDCA.

Plateaus, Switching, and De-escalation — Why plateaus at 60 to 68 weeks are physiology not failure, semaglutide to tirzepatide switch data, and the three-phase de-escalation framework for patients who want a pathway off medication.

Safety Concerns, Answered Directly — Pancreatitis risk in real numbers, why the pancreatic cancer association is not established in human data, the blood pressure paradox, and what sour food cravings tell you about zinc status.

Natural GLP-1 Support and Supplements — The most potent natural GLP-1 stimulus, foods and compounds with real evidence, the honest answer on berberine, Ozempic face and collagen, and a straight take on Pendulum's GLP-1 Probiotic Pro.

Your Content Cure

Register >>HERE<< to access the complete Q&A document with references, the full webinar replay, and the GLP-1 Toolkit.

Developed in collaboration with the Fullscript medical advisory team for educational purposes. Not intended as medical advice.

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