
Trying 2 Learn
Trying to cut through the advertisements and AI summaries while trying to learn today is difficult. We developed this podcast from 'The Why Science Initiative" to expand learning on any topic to the general public. This is the podcast where the target it to gain a deeper understanding of new research and interesting topics. Sponsored by Quansys Bio and Eagle Works Manufacturing, with Kyle Valgardson as the host.
Trying 2 Learn
Episode 18- Dr. Jessica Lancaster | Immunity & Aging, the Fibroblast T-cell Frontier
We often think of T cells as the body’s defenders—but what happens when they can’t move where they’re needed?
In this episode, immunologist Dr. Jessica Lancaster breaks down the overlooked role of fibroblasts—the structural cells that help (or hinder) T cell movement—and how this relationship impacts aging, immune function, and disease outcomes.
We explore:
- Why aging immune cells don’t just slow down—they get stuck
- The role of tissue environments in T cell surveillance and mobility
- How manipulating fibroblast–T cell interactions could unlock better therapies for cancer, infection, and age-related decline
This conversation zooms in on one of the most dynamic frontiers in immunology—and makes it accessible, without watering it down.