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The Egg Factor
Welcome to The Egg Factor, a podcast dedicated to exploring the latest research and developments in the field of fertility. Hosted by Dr. Norbert Gleicher, a world-renowned fertility specialist with over 40 years of experience, this podcast provides expert insights and advice for anyone interested in improving their chances of conceiving.
From the latest breakthroughs in reproductive technology to the best ways to optimize your fertility naturally, Dr. Gleicher and his team of experts cover it all. With a focus on evidence-based research and personalized care, The Egg Factor offers a unique perspective on fertility that you won't find anywhere else.
Whether you're just starting your fertility journey or you're looking for advanced solutions, The Egg Factor is the podcast for you. So tune in to stay up-to-date with the latest developments in the fertility industry and get expert advice on how to maximize your chances of conception.
The Egg Factor
Lean PCOS & Low Androgens: The Overlooked Diagnosis Sabotaging Fertility Over 35
Not all PCOS is created equal. In this solo episode of The Egg Factor, CHR’s Medical Director Dr. Norbert Gleicher dives into one of the most misunderstood—and frequently missed—diagnoses in reproductive medicine: lean PCOS with low androgens, also known as D-phenotype PCOS.
Often overlooked because these patients don’t fit the “typical” PCOS profile, women with D-phenotype are usually thin, have regular periods, and no obvious signs of excess androgens. But as they age—especially after 35—their androgen levels decline dramatically, quietly sabotaging their fertility. Many are prescribed inositol supplements that could actually make things worse.
Dr. Gleicher unpacks the science behind this phenotype, explains why standard protocols fall short, and offers guidance on how to recognize and treat this subtle but significant hormonal imbalance.
If you’ve been diagnosed with PCOS but don’t quite relate to the usual symptoms—or you’ve been told everything looks “normal” despite ongoing fertility struggles—this episode is a must-listen.
Available now on Spotify, Apple Podcasts, and all major podcast platforms.
Brought to you by the Center for Human Reproduction (CHR) on the Upper East Side of New York City. With over 40 years of experience and a history of innovation, CHR has been at the forefront of fertility care since the beginning.
Our founder, Dr. Norbert Gleicher, reported the first successful transvaginal egg retrieval in human history, helping to shape the future of IVF as we know it today. CHR is known for tackling some of the most challenging fertility cases—especially women over 40 and those with diminished ovarian reserve—by offering highly individualized, evidence-based care when others often turn patients away.
Our team has published more than 450 peer-reviewed research papers advancing reproductive medicine, reflecting our deep commitment not only to patient care but to the science that drives better outcomes. At CHR, you're never just a number. You're part of a community focused on giving you the personalized support, science, and hope you deserve.
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