The Egg Factor

Low AMH, High Hopes: Understanding DOR and Premature Ovarian Aging

Center For Human Reproduction

Hearing the words “low AMH” or “diminished ovarian reserve” can feel devastating, but they do not mean the end of your fertility journey. In this episode, Dr. Norbert Gleicher explains what ovarian reserve really means, how diminished ovarian reserve (DOR) and premature ovarian aging (POA) are diagnosed, and why early intervention and individualized care matter. He also shares how research has shaped treatment approaches, offering hope to women told they have little or no chance of success. 

Brought to you by the Center for Human Reproduction (CHR) on the Upper East Side of New York City. With over 40 years of experience and a history of innovation, CHR has been at the forefront of fertility care since the beginning.   

Our founder, Dr. Norbert Gleicher, reported the first successful transvaginal egg retrieval in human history, helping to shape the future of IVF as we know it today. CHR is known for tackling some of the most challenging fertility cases—especially women over 40 and those with diminished ovarian reserve—by offering highly individualized, evidence-based care when others often turn patients away. 

Our team has published more than 450 peer-reviewed research papers advancing reproductive medicine, reflecting our deep commitment not only to patient care but to the science that drives better outcomes. At CHR, you're never just a number. You're part of a community focused on giving you the personalized support, science, and hope you deserve. 

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