How a Canyon, a Calling, and a Group of Rebels Started a Movement That Saved Millions of Animals (#6 of Top Ten from 2025)

In this powerful conversation, Cyrus Mejia—one of the original founders of Best Friends Animal Sanctuary—shares the extraordinary origin story behind what has become the largest no-kill animal sanctuary in the country. From settling in a remote red-rock canyon with only $5,000 and a vision, to challenging a century-old system that routinely killed millions of shelter animals each year, Cyrus and his team proved that compassion, collaboration, and sheer grit could spark a national movement. He walks us through the early days of building a sanctuary from scratch, the spiritual energy of Angel Canyon, and how Best Friends evolved into a nationwide force with data-driven strategies, partnerships, and on-the-ground teams supporting shelters across the U.S.

Cyrus also dives into the emotional and philosophical side of the work—how art, kindness, transparency, and community form the backbone of true social change, and how he stays grounded in the face of overwhelming need. He offers wisdom on avoiding burnout, navigating group dynamics, and finding meaning and moxie in purpose-driven work. Whether you’re an animal lover, a volunteer, or someone searching for deeper purpose in midlife and beyond, this conversation is a moving reminder that ordinary people, armed with compassion and conviction, can change the world one life at a time.

Cyrus's Info:

https://www.cyrusmejia.com/about-the-artist

https://bestfriends.org/

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