Going anti-Viral

Cognitive Aging in HIV: Clinical Assessment and Management – Dr Shibani Mukerji

Going Anti-Viral Season 1 Episode 75

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0:00 | 37:22

In episode 75 of Going anti-Viral, Dr Shibani Mukerji joins host Dr Michael Saag to discuss a presentation she gave at the 2026 Conference on Retroviruses and Opportunistic Infections (CROI) entitled Cognitive Aging in HIV: Clinical Assessment and Management. Dr Mukerji is an Associate Professor of Neurology at Harvard Medical School and is a practicing neurologist in the Department of Neurology and Division of Infectious Diseases at Massachusetts General Hospital. Her research focuses on HIV pathogenesis in the central nervous system and her clinical focus is neurology-infectious diseases, with specific interests in neurological complications and aging in people living with HIV. Dr Mukerji shares her journey in neurology, her research on HIV and neurological complications, and insights into brain health in aging populations, especially those with HIV. Dr Mukerji and Dr Saag offer practical approaches to cognitive assessment, sleep, mood, and movement issues, emphasizing a longitudinal, patient-centered model of care. 

0:00 – Introduction 

2:07 – Dr Mukerji 's journey in neurology and infectious diseases

7:39 – Cognitive aging in HIV: clinical assessment and management

13:26 – Understanding cognitive health in HIV patients

18:29 – Assessment and management of depression, sleep, and movement disorders 

26:26 – Impact of hearing loss and emotional health on cognitive impairment

31:15 – The Valcour tripod: cognitive, motor, and mood assessment

34:15 – Future directions in HIV and neurology research

Resources

CROI 2026: https://www.croiconference.org/

View Dr Mukerji 's presentation at CROI 2026: https://www.croiwebcasts.org/p/2026croi/croi/20 

View Presentation by Dr Victor Valcour at CROI 2019: https://www.croiwebcasts.org/p/2019croi/159 

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Produced by IAS-USA, Going anti–Viral is a podcast for clinicians involved in research and care in HIV, its complications, and other viral infections. This podcast is intended as a technical source of information for specialists in this field, but anyone listening will enjoy learning more about the state of modern medicine around viral infections.

Going anti-Viral’s host is Dr Michael Saag, a physician, prominent HIV researcher at the University of Alabama at Birmingham, and volunteer IAS–USA board member. In most episodes, Dr Saag interviews an expert in infectious diseases or emerging pandemics about their area of specialty and current developments in the field. Other episodes are drawn from the IAS–USA vast catalogue of panel discussions, Dialogues, and other audio from various meetings and conferences.

Email podcast@iasusa.org to send feedback, show suggestions, or questions to be answered on a later episode.

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