
One in Six Billion
A podcast about diabetes and genes hosted by Andrew Hattersley and Maggie Shepherd.
One in Six Billion
Special episode 5. John Dennis. Research breakthrough in Type 2 diabetes treatment.
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Andrew Hattersley and Maggie Shepherd
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Season 3
We talk to John Dennis, a data science researcher working in the University of Exeter. He used data from 1 million people with Type 2 diabetes to discover how the clinical characteristics of a patient alter the glucose lowering with different treatments. John’s 5 drug model, published in the Lancet in late February 2025, uses simple clinical information to identify, for the first time, the best glucose lowering treatment for a patient. The model selected best treatment lowers the glucose most, doubles the time before another medication is needed and reduces long term complications of diabetes. See www.1in6b.com for more details.