One in Six Billion
A podcast about diabetes and genes hosted by Andrew Hattersley and Maggie Shepherd.
One in Six Billion
Series 4 episode 7. Sarah Richardson. Small extra-islet beta cells matter
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Andrew Hattersley and Maggie Shepherd
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Season 4
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Episode 7
Sarah Richardson talks about her new exciting research on insulin producing beta-cells that are single cells or small clusters rather than in islets. These extra-islet beta-cells make up most of the insulin producing capacity of the pancreas in young children and are particularly susceptible to immune attack in Type 1 diabetes. This important research explains why the loss of insulin producing cells in Type 1 diabetes is more severe in young children and informs future work on treating and preventing Type 1 diabetes.