The MycoGeeky Podcast

How Magic Mushrooms Got Their Genes—and Their Names with Edward Grand PhD

mycoGeeky Season 4 Episode 7

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Join us for a deep dive into the science and mysteries behind psilocybin-producing mushrooms with mycologist Edward Grand, PhD. We’ll explore groundbreaking research, fungal genetics, and the ongoing debates in taxonomy—connecting cutting-edge science to the world of at-home cultivation.

📚 Featured Papers Discussed:
 • “Horizontal Gene Cluster Transfer Increased Hallucinogenic Mushroom Diversity” (Reynolds et al., 2018) — Discover how psilocybin-producing genes spread across species through horizontal gene transfer (HGT).
https://pmc.ncbi.nlm.nih.gov/articles/PMC6121855/pdf/EVL3-2-88.pdf

 • “Molecular Karyotype of the White Rot Fungus Pleurotus ostreatus" (Larraya et al., 1999) — Learn how genome mapping in oyster mushrooms reveals the complexities of fungal evolution.
https://journals.asm.org/doi/10.1128/aem.65.8.3413-3417.1999
 • International Code of Botanical Nomenclature (ICBN): Who decides fungal names, and how do Lumpers vs. Splitters shape taxonomy?
 • AFLP (Amplified Fragment Length Polymorphism): How genetic fingerprinting helps identify fungal strains and track successful monokaryon matings.

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