Welcome to our latest podcast episode where we peel back the layers of adult acne, diving deep into the science behind this common yet often misunderstood skin condition. From the humble beginnings of puberty to the complex factors contributing to acne formation, we explore the journey from zits to treatments. Join us as we dissect the role of sebaceous glands, the impact of hormonal imbalances, and the microbial mayhem within our skin microbiome. With insights into the latest treatments, including topical agents and systemic therapies, we navigate the path towards clearer skin and improved confidence. Tune in for a comprehensive discussion on acne and its management, shedding light on the quest for a future free from breakouts and blemishes.

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References:
Barbieri, J. S., Wanat, K., & Seykora, J. (2014). Skin: basic structure and function. https://www.sciencedirect.com/referencework/9780123864574/pathobiology-of-human-disease

Das, S., & Reynolds, R. V. (2014). Recent advances in acne pathogenesis: implications for therapy. American journal of clinical dermatology, 15, 479-488. https://link.springer.com/article/10.1007/s40257-014-0099-z

Del Rosso, J. Q., & Kircik, L. (2024). The cutaneous effects of androgens and androgen-mediated sebum production and their pathophysiologic and therapeutic importance in acne vulgaris. Journal of Dermatological Treatment, 35(1), 2298878. https://www.tandfonline.com/doi/full/10.1080/09546634.2023.2298878

Dréno, B., Pécastaings, S., Corvec, S., Veraldi, S., Khammari, A., & Roques, C. (2018). Cutibacterium acnes (Propionibacterium acnes) and acne vulgaris: a brief look at the latest updates. Journal of the European Academy of Dermatology and Venereology, 32, 5-14. https://doi.org/10.1111/jdv.15043

Mayslich, C., Grange, P. A., Castela, M., Marcelin, A. G., Calvez, V., & Dupin, N. (2022). Characterization of a Cutibacterium acnes Camp Factor 1-Related Peptide as a New TLR-2 Modulator in In Vitro and Ex Vivo Models of Inflammation. International Journal of Molecular Sciences, 23(9), 5065. https://doi.org/10.3390%2Fijms23095065 

Mayslich, C., Grange, P. A., & Dupin, N. (2021). Cutibacterium acnes as an opportunistic pathogen: An update of its virulence-associated factors. Microorganisms, 9(2), 303.