When the hot water went out, you might call a plumber, but if the water heater is out it might instead be an electrical problem - just like how heart problems can stem from faulty electrical signals rather than the heart muscle itself. Atrial fibrillation (AFib), the most common arrhythmia affecting six million Americans, disrupts the heart’s electrical system, causing rapid, chaotic beating that increases stroke risk fivefold. In this week's episode, we review AFib, the risk factors to develop it, symptoms , how it happens, and treatments. Water you waiting for, listen today!

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References:

Heijman, J., Voigt, N., Nattel, S., & Dobrev, D. (2014). Cellular and molecular electrophysiology of atrial fibrillation initiation, maintenance, and progression. Circulation research, 114(9), 1483-1499. https://www.ahajournals.org/doi/full/10.1161/CIRCRESAHA.114.302226

Lip, G. Y., Fauchier, L., Freedman, S. B., Van Gelder, I., Natale, A., Gianni, C., ... & Lane, D. A. (2016). Atrial fibrillation (Primer). Nature Reviews: Disease Primers, 2(1). https://www.proquest.com/scholarly-journals/atrial-fibrillation-primer/docview/2711094799/se-2?accountid=14690

Lloyd-Jones, D. M., Wang, T. J., Leip, E. P., Larson, M. G., Levy, D., Vasan, R. S., ... & Benjamin, E. J. (2004). Lifetime risk for development of atrial fibrillation: the Framingham Heart Study. Circulation, 110(9), 1042-1046. https://www.ahajournals.org/doi/full/10.1161/01.CIR.0000140263.20897.42

Munger, T.M., Wu, L.Q., Shen, W.K..(2013).  Atrial fibrillation. J Biomed Res.28(1):1-17. doi: 10.7555/JBR.28.20130191. https://pmc.ncbi.nlm.nih.gov/articles/PMC3904170/

Koren, M.J., & Sanghvi, N. (14 June, 2023). Two docs talk A-fib. On MedEvidence! Truth Behind the Data. [Podcast]. https://medevidence.com/two-docs-talk-a-fib-1

Wijesurendra, R. S., & Casadei, B. (2019). Mechanisms of atrial fibrillation. Heart, 105(24), 1860-1867. https://heart.bmj.com/content/105/24/1860.abstract

Yao, Y., Yang, M., Liu, D., & Zhao, Q. (2022). Immune remodeling and atrial fibrillation. Frontiers in Physiology, 13, 927221. https://www.frontiersin.org/journals/physiology/articles/10.3389/fphys.2022.927221/full