Beneath the Surface of Hidradenitis Suppurativa

MedEvidence Articles

MedEvidence Articles
Beneath the Surface of Hidradenitis Suppurativa
Jul 07, 2025
MedEvidence Articles

In this week's episode, we explore the chronic inflammatory skin condition Hidradenitis Suppurativa (HS). With HS, hair follicles located in large skin creases like the armpits become inflamed and clogged. The units, called the pilosebaceous unit, fill with puss, rupture, and cause a host of problems for sufferers. We investigate what hidradenitis suppurativa is, who it affects, what goes wrong in the body, and what's being done about it.


References:
Schramm, E. & Bernhardt, M. (11 June, 2025). Modern Medicine is Transforming Hidradenitis Suppurativa Treatment. On MedEvidence! Truth Behind the Data. [Podcast]. https://medevidence.com/modern-medicine-is-transforming-hidradenitis-suppurativa-treatment

Ballard, K., & Shuman, V. (2024). Hidradenitis suppurativa. StatPearls. https://www.ncbi.nlm.nih.gov/books/NBK534867/

Saunte, D. M. L., & Jemec, G. B. E. (2017). Hidradenitis suppurativa: advances in diagnosis and treatment. Jama, 318(20), 2019-2032. https://jamanetwork.com/journals/jama/article-abstract/2664466

Jemec, G. B. (2012). Hidradenitis suppurativa. New England Journal of Medicine, 366(2), 158-164. https://www.nejm.org/doi/full/10.1056/NEJMcp1014163

Sabat, R., Alavi, A., Wolk, K., Wortsman, X., McGrath, B., Garg, A., & Szepietowski, J. C. (2025). Hidradenitis suppurativa. The Lancet, 405(10476), 420-438. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)02475-9/fulltext