The Many Faces of Cancer

Redefining Life with Incurable Cancer with JJ Singleton

Melissa Grosboll Episode 134

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0:00 | 42:29

When JJ Singleton was just 27 years old, he was diagnosed with colorectal cancer—a disease he believed only affected older adults. After surgery and chemotherapy, he thought cancer was behind him. Just weeks later, it returned.

Today, more than a decade later, JJ is living with stable but incurable cancer after a clinical trial became the treatment that changed—and ultimately saved—his life.

In this inspiring conversation, JJ shares what it's like to live with cancer long-term, the emotional toll of isolation, why patients must become their own advocates, and how breakthroughs in biomarkers, immunotherapy, and clinical trials are changing the future of cancer care.

In this episode, we discuss:

  •  JJ's colorectal cancer diagnosis at age 27 
  •  Ignoring symptoms because "I'm too young for cancer" 
  •  Losing 80% of his colon 
  •  When cancer returned only weeks after chemotherapy 
  •  Living with stable but incurable cancer for over ten years 
  •  The clinical trial that became his lifesaving treatment 
  •  Why biomarkers and personalized medicine matter 
  •  How AI is beginning to improve cancer care 
  •  The unique challenges of rural cancer patients 
  •  The importance of finding community after diagnosis 
  •  Why patients should ask more questions and advocate for themselves 
  •  Finding balance instead of trying to do everything "perfectly" 
  •  The future of clinical trials and targeted therapies

Whether you're a patient, survivor, caregiver, or simply someone wanting to better understand today's cancer landscape, this episode is filled with hope, honesty, and practical wisdom.

Resources:

JJ's Instagram: https://www.instagram.com/jj5145?igsh=cTA4YnhsajI2NTU=

JJ's Tiktok: https://www.tiktok.com/@jjsingleton32?_r=1&_t=ZP-97ST10psUxS

JJ's X: https://x.com/JJSingleton1

JJ's LinkedIn: https://www.linkedin.com/in/jj-singleton-a275ab2a4/

OncoDaily 2026 100 Most Influential Cancer Survivors

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