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Regenerative Medicine Insights Including Stem Cells & Molecular Hydrogen Healing with Mick Emandi

Pamela Wirth

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0:00 | 27:38

Mick Emandi is the CEO of Regen MDs, a regenerative medicine practice focused on helping people with chronic pain and complex health conditions regain their quality of life. Working alongside a team of world-class physicians, he helps bring innovative therapies and breakthrough treatment technologies to patients dealing with joint, neurological, autoimmune, and heart-related conditions. Over the past nine years, Mick and his team have helped more than 30,000 people achieve meaningful health improvements while generating over $70 million in revenue through advanced regenerative care solutions.  


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SPEAKER_02

Hi, this is Pamela Worth with the Hello Health Podcast, and today I have to make a Monday and one of your doctors, and uh really looking forward to understanding more about regenerative health.

SPEAKER_00

Thank you for having us, Pamela. I have Dr. Greg Carter on the line.

SPEAKER_01

Thank you for having us on your show, Pamela.

SPEAKER_02

Absolutely. So there's a lot of discussion around re regenerative medicine. I mean, there's there's energy, there's injections, there's um peptides, stem cells, IVs. Talk to us about you know what is what is real, what is not, what's what you're finding is actually um proving to be effective.

SPEAKER_00

Yeah, no, uh absolutely. Well, you know, there are a lot of conditions that a lot of people have been uh having to give up hope on. You know, neurodegenerative conditions, you know, the bad knee that you don't want surgery on, the bad shoulder that you refuse to have surgery on, or your your parents or your husband's parents um are struggling with these kind of conditions. You know, you have cardiovascular disease, you have so many systemic conditions like autoimmune, um, things like things of that nature. And you know, the world of stem cells has just opened up, it's really blossomed, and there's a lot of benefits to stem cells. The challenge with the current uh state of stem cells is that it doesn't do everything for everybody. Uh, the reason being is uh typically stem cells come from one of many areas of the placenta. Most people are familiar with stem cells coming from the umbilical cord, for example. Uh, some of you might have heard about stem cells coming from Wharton's jelly. Now, those are just two of the six areas of the placenta, and each of the areas has their own unique properties that are involved in taking making an embryo into a human being over nine months. So there's a new technology now. It's called Ultra RSF. RSF standing for regenerative signaling factors. And uh, I'm gonna have Dr. Greg talk to you about how things have changed from the world of stem cells and exosomes to what we have today.

SPEAKER_01

Um, okay. Uh, Pamela, thank you once again. Um, so as Mick elucidated, we are now in the fourth generation of regenerative medicine. Um, it represents a quantum leap forward in what we uh previously had discovered. Remember, the first generation was something called platelet-rich plasma, where we pulled out our own blood, spun it down, and then the little gold liquid was um supposed to be filled with growth factors and cytokines that helped the body. Great on paper, but it was a little bit underwhelming in its performance. Um, when we got into the 70s, uh, man started utilizing embryonic stem cells, and they worked amazing. Um, very high success rate. The problem is they come from aborted fetal tissue, and nobody wants that, and certainly not in America. Um, so from the 1970s to the 1990s, science sought to find a different source of stem cells. And in 1991, a doctor, Dr. Andrew Kaplan, he published a paper that said we can get mesenchymal stem cells that do exactly the same thing as embryonic stem cells, not from uh fetal tissue, but from the placenta, and it'll have the same exact success success rate. So from basically from uh 1991 until 2017, everybody, including me, uh all of my friends in uh anti-aging medicine were utilizing mesenchomal stem cells and their progenitor um exosomes. The problem is these things had about a 30% success rate. There's a number of reasons for that, and people started uh pressing Dr. Kaplan, hey, what's going on? You know, you said that this was going to be exactly like it. And in uh 2017, uh Dr. Kaplan had a uh had a had an attack of conscious, and he stood up in front of the American Medical Association after he published a paper and he said, Hey, I I I basically lied. Mesenchomal stem cells do not do the same thing, they do a very similar thing. Um, and what they do is they deliver the peracrine signals that are responsible for doing the heavy lifting. Um, so in fact, the stem cell and the exosome are just delivery systems. And the problem with these delivery systems is in order to harvest them from the placenta, we're utilizing technology from the 80s and the 90s. And now in 2026, 2025, going just a few years back, our technology is orders of magnitude superior to that. So one of the problems with stem cells is the stem cell itself is what we all conceptualize as doing the heavy lifting. It's just a ball of DNA, somebody else's DNA, carrying the secretome or the pericron signals of, as Mick said, only one section of the six geographies of the placenta that carry all 312 um regenerative cell lines. And each cell line has dozens to hundreds of regenerative signaling factors in them. And so, if, say for instance, um one the one section that the clinic is utilizing is only indicated for ligamentous, tendinous, and cartilaginous structure, but that patient is trying to deal with um Parkinson's Alzheimer's or dementia, these programming languages do not communicate. And so it doesn't matter how much stem cells are introduced to the body, it's got to be the right stem cells for the target tissue that we're trying to fix. So, one of the advantages of utilizing regenerative signaling factors is comes from the entire source code, all six regions, all 312 cell lines of the total secretome, and there's no genetic material. There's no DNA and there's no RNA. It's just the signals themselves. And because it's just the signals themselves, there's no danger of any kind of aberrants with DNA like graph versus host disease or autoimmune with exosomes because that can happen. It's a very real thing. So, also because we're utilizing this 21st century technology, we are able to preserve many of the factors and cofactors that nature has embedded in the placenta for reproduction that is being repurposed in science for regeneration for adults like us. Um, a couple of those key factors are number one, it will move the body from a state of redness, pain, heat, and swelling, inflammation, right, to a state of anti-inflammation. So rest and recover. The problem is this the macrophage that's causing the redness, pain, heat, and swelling called the M1 macrophage, never gets the biochemical electrical signal to go ahead and transition from M1 to M2 because of disruptions in the EMF in our environment, like Wi-Fi, Bluetooth, um, the uh the my favorite uh neurotoxin, MSG and Doritos, things of that nature. And then so this M1 to M2 shift never happens. So this acute inflammation, whose only job is for 72 hours to tell the person, sit down under this tree, eat a peach, and don't move. We're gonna inflame the area to keep it stable, and then we're gonna call out to the body anybody that can fix this knee, we need you to swim here. We need you to amass around the border of the inflammation. And in about three days, I'm gonna drop this wall of inflammation. I need all of you to flood in and repair this knee, but that signal never happens because of aberrances in our environment. And that acute inflammation becomes subacute, then it becomes chronic, and the chronic inflammation, as you know, Pamela, just becomes an ongoing problem. There's a number of other really incredible beneficial components to regenerative signaling factors when you can utilize the entire secretome, like with ultra RSF, um, but that's uh on the surface.

SPEAKER_02

Wow. Okay, so with this in mind, what types of stem cells would you do for like an inflamed knee versus like an autoimmune disorder, right? I mean, one's got to be potentially like an injection versus one's more like an IV, or talk to us about that.

SPEAKER_01

Yeah, so what you're referring to is where would we deliver it? Would we deliver it intra-articulately or would we do it through an IV or would we do it intranasally? And the reality is, is what is the target tissue? Now, here's the beautiful part about regenerative signaling factors, as nature created them right out of the placenta, they have something called chemotaxis. It's just a fancy medical way of saying, regardless of where you put them in the body, because of this thing called flix law of diffusion, they will swim through the body and they will only land on and bind to the specific structures that are indicated for their programming language. So if what's going on is the person's immune system is malfunctioning, those mechanical components of the body that are responsible for regulating the immune system are gonna be upregulating these things called damps or little like satellite dishes in the body that are going, help us Obi-Wan Kenobi, we're damaged over here. And here come a big cloud of regenerative signaling factors, and the only ones that are gonna paratroop out are gonna be the ones for the autoimmune tissue. In the knee, only the ones that are specific for the structures of that knee are gonna jump out there. And what's really beautiful about this is exosomes have a life in the body of about 72 hours. Stem cells, under perfect conditions, have a life in the body of about five to seven days. Because these are coming directly from the placenta. Number one, they last up to 28 days. And that's important because human beings operate in 28-day cycles, right? We take 10, 28-day cycles, we go from clump of cells to a baby, okay? So in the repair process of the body, you have to think in three sections: repair, rebuild, remodel. Each one takes 28 days. So if we know that the regenerative signaling factor is not only gonna bond to the specific tissue, but for 28 days, it's gonna pump it full of the instructions, the work order, the supervisor, everything that's necessary for your tissue to rebuild itself, it's gonna do it for 28 days, exactly as nature would do it. So not only will it float through the body and find the specific target tissue, but it will bind to that tissue and it will start the healing process along every gradient that you would want, like angiogenesis, uh, et cetera. Does does that answer your question?

SPEAKER_02

Yeah, no, I think it's fascinating. So do you do you offer all different types of um uh trying to think of the right word?

SPEAKER_01

Um delivery systems we do. Yeah, because it's all one thing. It's it's a it comes in a vial, and because of because of the advancements in technology, you don't have to have one of those negative 80 degrees,$38,000 freezers um for stem cells because those are very fragile and these are very stable. Okay, because they come directly from nature.

SPEAKER_02

Now, um, are all of yours sourced from just one place, one country, one type of population? Talk to us.

SPEAKER_01

I'm gonna let Mick answer this because it is a fascinating story.

SPEAKER_00

So, yeah, um, we spent about three years in identifying, well, not me, but uh my colleague who um has the patents on this. Um, he spent about three years uh looking for the perfect donor, went through about 3,000 donors and found the perfect donor in Alabama, 18-year-old girl who was uh pregnant. And uh due to religious reasons, she never had a single vaccine in her life, never had COVID, never had a COVID vaccine, almost no microplastics. When she had a healthy childbirth, they were able to take it to their tissue bank in Oklahoma City, Oklahoma, and their FDA registered uh lab and be able to um extract the stem cells from each of the six areas of the placenta, essentially be able to um then extract the actual signaling factors uh through a special process that they have uh that's patented and be able to uh remove all DNA and RNA from that byproduct of proteins, growth factors, chemokines, peptides, proteins, and uh basically lyophilize it into a freeze-dried product. Like a lot of people are familiar with peptides nowadays, uh, the powdered stuff in those little vials. Well, this is also powdered, but it's actual uh protein from a placenta, and it does not have any biological product in it, doesn't have any DNA and RNA, so it's completely acellular. So it can actually be liophilized, and when it's reconstituted just with sterile water, it's 99.8% bioavailable. And they can inject it at home at their kitchen table, you know, it directly into their knee, directly into their uh belly fat, just like they do a GLP1. They're able to inhale it intranasally just like they would an affrine spray. And think of that stem cell technology going directly into your brain tissue. That's pretty powerful. And uh, you know, a lot of the reasons why people go overseas for stem cells is because in Florida in the United States, um, you know, systemic IVs are banned uh with stem cells or exosomes because they're considered a biologic. This is not a biologic, it's an acellular product. So we can literally um ship the product directly to our patients. Our nurses and our medical team would guide uh the patient through administration at home, self-administration at home. They don't even have to come to our offices in Florida unless they absolutely wanted to come in for an intra-articular injection of you know hyaluronic acid and this um uh uh stem cell product, also, which is amazing, by the way, in getting uh trim such amazing results in just days. Uh, but you know, across the board we've had uh amazing results from our patients, whether it be neurodegenerative conditions such as Alzheimer's, Parkinson's, uh people with um uh uh knee pain, shoulder pain, neck pain, back pain. Um, it's amazing how when Dr. Greg was talking about that M2 to M M1 to M2 shift, that's what's missing right now in modern medicine. There's nothing that does this. And there's a part of the stem cell, um, sorry, there's a part of the placenta that is specifically designed to do this, and that's the amnion. And so nobody has access to the amnion when they use a um umbilical cord stem cell. There's no there's no amnion in a Warton's jelly stem cell. So because this is able to use the growth factors and the uh peptides from all six areas of the placenta, we're able to uh access the amnion as a part of this um this uh delivery mechanism.

SPEAKER_02

Yeah, it's fascinating. So these clinics are popping up all over the place, right? And many of them will tell you before you get an IV, you should get the body to a better state, whether that's through like the PEMF or ozone or um some of these like lymphatic drainage type solutions. What are your thoughts on this? You know, helpful.

SPEAKER_00

So this is yeah, so this is our hydrogen device just like this. And you can see my hydrogen machine right here. That one device we're using across the country for people with neurodegenerative conditions, and just by pressing start, now I'm breathing pure hydrogen gas. And this is more powerful than everything that you just said. In just 15 minutes, it's like having a th eating a thousand blueberries, and so it's written in one hour. I'm basically neutralizing every single free radical in our body from my head to my toe, all 36 trillion. This is the most powerful gas that is able to neutralize all of the free radicals that are generated by all the toxins in our body, and these toxins are going after our healthy cells and causing oxidative stress, too much oxidative stress leads to inflammation. And what is everybody trying to treat? Inflammation, right? So, this is getting to the root cause of all diseases. Any condition that your viewer is dealing with, if they just went to Google right now and just typed in the word molecular hydrogen and their particular condition, whether it be heart disease, COPD, stroke, Alzheimer's, autoimmune, they'll find a wealth of information pop right up and all the clinical studies supporting how hydrogen can help their condition by itself. Now, what we do is we use the hydrogen to bring down that oxidative stress and that inflammation throughout their body so that that's the primary, that's the initial treatment for all of our patients. And the secondary treatment is this stem cell technology where it's actually going to start regenerating and healing a lot faster than just the hydro hydroheal uh hydrogen inhalation device alone.

SPEAKER_02

Can I add to that? No, yeah, please go ahead.

SPEAKER_01

So, what's very interesting about all of those modalities that you mentioned is we have repurposed things like PMF, um, we've isolated red light, we've isolated um superphysiologic amounts of blutathione, right? Because we know that if we if we isolate these waveforms, if we isolate these nutrients, um if we introduce them to the body in a in a way that is not natural, like hyperbaric oxygen therapy, right? That it'll have a beneficial effect on inflammation. What's fascinating about this is you're not going to go anywhere in nature from the dawn of time till today and be exposed to PMF or hyperbaric oxygen. However, in 2007, when the University of Osaka discovered the beneficial use of molecular hydrogen as a molecular gas, and the subsequent 3,000 studies that have ensued since then, it has been discovered that man was specifically designed to utilize molecular hydrogen as a de facto essential nutrient. A nutrient is something that's going to feed our energy. An essential nutrient is going to feed our biochemical reactions. So taking something from catalyst to end product, that end product becomes a catalyst for the next thing, on and on and on and so on. Apparently, during the Paleolithic period when man was designed, we were eating these things called raw organic fruits and vegetables, which I never get. Okay. And those raw organic fruits and vegetables were growing in mineral dense soil in an unpolluted atmosphere that simply does not exist anymore. And it would interact with our unpolluted microbiome, who apparently the 18-year-old girl in Alabama is the only person on planet Earth that still had it because she lives out in the Catskill Mountains. Okay. And the interaction of this pure organic fiber with an unpolluted microbiome is clouds and clouds and clouds of molecular hydrogen. So it's it's a fascinating study in that nature accommodated for this as an essential nutrient, essential meaning your body can't create it. And if you don't have it, all kinds of things go wrong, just like vitamin C. We can't create collagen without vitamin C. Bears can create it in their liver. I don't know why they need it. They seem to be doing okay. All right, but we can't create it, neither can we create molecular hydrogen, nor can you get it from water, nor can you get it from the atmosphere. It has to be from that specific source or the technology of the 21st century. And what is really the issue is the technology of the 21st century that I love Wi-Fi, Bluetooth, air conditioned, Starbucks, is the double-edged sword of it is too much of a good thing, is toxic to the body. So we have to leverage technology to offset the convenience of our Epicurean lifestyle.

SPEAKER_02

No, it's expensive. So then do you recommend how often do you recommend somebody breathing in the molecular hydrogen?

SPEAKER_00

So, Pamela, um, you know, the molecular hydrogen breathing it in from a wellness perspective, two to three times a week is sufficient, like for 30 minutes. Uh, you know, a lot of people are familiar with hydrogen water that's gotten a lot of um uh press for biohackers in the last year. Uh, Gary Brecka, so a lot of people have heard of him. People have heard of Joe Rogan and uh um uh you know Andrew Huberman, and they all talk about how hydrogen water is great. And most of the clinical studies were with hydrogen water and they showed amazing efficacy, but there's only a minuscule amount of hydrogen in hydrogen water. In one full bottle of hydrogen water, if they were to use those hydrogen tablets or those hydrogen water bottles, you only can fit in due to physics, you can only fit in 0.8 milligrams of hydrogen. In just 15 minutes of this machine that I have right next to me that I use every day, um, we are getting 800 milligrams of molecular hydrogen. So if you were to divide 800 by 0.8, you'll get to a number of around a thousand. So a thousand bottles of hydrogen water equate to just breathing it in in just 15 minutes. In 15 minutes, people will have an amazing uh experience with their sleep at night, uh deeper REM sleep, faster time to sleep, amazing mental clarity and a boost in their energy because it supercharges the mitochondria while at the same time neutralizing all the free radicals that are causing all the oxidative stress, which nothing in nothing that you and I are doing today other than this molecular hydrogen is going to help resolve. We all are familiar with taking vitamins A, C, and E as antioxidants, and you know they're all well and good, but you know, think about it you're producing a one billion free. Radicals a day. Do you really think a little pill is going to knock them out every day and counteract all the damage that your body is with all the toxins in our body? Do you really think those little capsules are really doing that much? Not really. You know, so that's that's the challenge, right? You know, we want to stop the aging process, slow stop, slow stop and reverse the aging process. Um, there's a double-blind placebo control trial that was done just a few years ago, whereby healthy 70-year-olds they were drinking very, very high doses of hydrogen over a period of six months. And at the end of six months, all of them had significant improvements in their uh age-related biomarkers, and the length of their telomeres increased by uh uh to 15% over the placebo group, which basically means it's the first and only controlled trial to show a um significant defined improvement in telomere length um in history.

SPEAKER_02

That was fascinating. So would you recommend different uh doses, if you will, for a regular person versus like an athlete versus somebody with cancer versus somebody immune or autism?

SPEAKER_00

Talk to us a little bit. We have three, we have four grades of because we're we're obviously in the medical field. So, you know, we have hundreds and hundreds of wellness centers and longevity doctors that use it strictly for wellness, but then when their patients present to them that they have cancer, or you know, one at least 50 to 70 percent of patients in every any wellness setting are there because they have health challenges. And for those health challenges, you know, two to three times a week is not going to cut it. You know, they really need um, you know, we have grades, grade one, two, three, and four. So if you say had grade one um uh, you know, of a medical condition, then you're looking at one hour twice a day in addition to drinking the water, uh, the hydrogen water, which the device also makes. Um, it grade two would be two hours twice a day, grade three, three hours twice a day. Grade four would be somebody that is a terminal condition. Um, you know, they're not doing anything else, so four hours twice a day is not that intrusive when they're sitting around watching TV or sitting around, you know, in their bed anyway. So it's very, you know, I put it on for six, eight hours when I'm sitting here on my phone working in at the office, also. So it's not very intrusive, it's very easy to do. And we also have the technology where we can actually um we actually have headphones where it pushes the hydrogen gas through the ear canal into the brain tissue. So it helps with hearing issues, with the brain issues, neurodegenerative conditions we were talking about. Patients that just had a stroke, for example, when they put these headphones on, it's miraculous how quickly they recover from a stroke because we're actually rehealing their ischemic reperfusion injury that they suffered. And so, you know, just like that, you know, for Alzheimer's patients, we're melting away the amyloid plaque buildup on the substantia nigra. We're substantially reducing that inflammation throughout the brain tissue, we're regenerating their neuronal cells so they can actually recover from their condition once they um stop the progression of it. So it's it's not an overnight thing, it it is something that takes several months. But anybody that wants to know more can just go to Google and just type in molecular hydrogen and their condition, and they'll be they'll be shocked and amazed at how powerful it is. Ours is a medical grade unit that has a lifetime warranty. Nobody in the world offers that. Um, you know, I have a medical practice with over 40 locations in Florida, over 30,000 patients, and I use it for my own patients also. So um, so for that reason, you know, we know that it works, and we have thousands and thousands of patients who just it's changed their lives.

SPEAKER_02

Okay, fantastic. Any other things you want to touch on or things you want to make sure that people know how to find you? Um to get more information.

SPEAKER_01

Can I expand on one point that Mick made?

SPEAKER_02

Yeah.

SPEAKER_01

Um, because we have we have a lifetime warranty, because Mick has taken the time to have the engineers put a solid block of platinum, which is the metal necessary for the electrolysis to separate hydrogen from oxygen. Now, other devices, um, and I'm not trying to be disparaging, it's just a matter of fact, they don't have a solid block of platinum. What they have is a block of some type of metal, a heavy metal like steel, wrapped in a membrane of platinum. And that platinum membrane degrades over an arc of time, usually about 100 hours. And now the person's only breathing in heavy metals. So it'll still bubble, it'll the bells and whistles will still go off, but no molecular hydrogen is being produced anymore, and all that the person is inhaling is heavy metal toxicity. And so, you know, we would be humbled and honored if you, you know, chose the hydroheal device. Um, I'm just saying, you know, we do have a lifetime warranty, nobody else does, because Mick has taken the time to have the engineers put a solid block in there so that particular um danger never occurs to our patients. And Mick, do you want to give contact info?

SPEAKER_00

Yeah, yeah. So um contacting is very easy. We have a pretty website uh so people can uh learn more about our protocol. Uh regenmds, r-e-g-en m d s dot com.

SPEAKER_02

Thank you both so much. It's really informative. There's so much to people to take in and learn and and uh can can really start to heal. So thank you so much.

SPEAKER_00

Thank you so much for that. Thank you, man.