hey real quick

Dire Wolves

Amy Goodgame & Marty Booth Episode 51
Speaker 1:

Hey, welcome to hey Real Quick. Well, I try not to read the news.

Speaker 2:

Oh yeah, I don't like it.

Speaker 1:

We don't need to say it, but there is one thing that has come out in the last. I guess it was the last week. It's mid-April right now.

Speaker 2:

Right.

Speaker 1:

About scientists. I'm hoping it's scientists bringing back the dire wolf.

Speaker 2:

Yeah, like in Game of Thrones, right the really big one, yeah, like the super size.

Speaker 1:

So you know I mean.

Speaker 2:

That's what we need right now is dire wolves.

Speaker 1:

I guess Let them loose. I don't know, but Can't hurt?

Speaker 2:

Yeah, it can.

Speaker 1:

Yeah, well, you know, I was in college when Jurassic Park came out, the first one.

Speaker 2:

Yeah, I feel like we know where this is going.

Speaker 1:

Yeah, we already saw it.

Speaker 2:

That's why we have zoos.

Speaker 1:

Yeah.

Speaker 2:

If you want to see an animal go.

Speaker 1:

Right Go to the zoo and we don't need to bring back any more. There's already lions in there.

Speaker 2:

There's already you know Bengal tigers, yeah, well, yeah, the company that did this, I don't know, was Colossal Biosciences, which sounds like maybe the evil corporation that did it in Jurassic Park.

Speaker 1:

I don't know. I know Colossal.

Speaker 2:

Yeah, it does Sorry Sounds like a colossal mistake to mess with Mother Nature.

Speaker 1:

Yeah, and I don't know. There's a lot going on. Did this project need to be, you know, april 2025? I don't think so.

Speaker 2:

And there's no telling how long they've been working on it.

Speaker 1:

Oh my goodness, Can you imagine yeah?

Speaker 2:

It says there. Well, the first thing from the article is the dire wolves were born by colossal biosciences. Are super cute and growing into stately animals? I don't think super cute no I mean they are when you look at the picture but isn't everything.

Speaker 1:

Isn't a puppy cute? Isn't everything? A baby lion is cute, but then it's gonna eat your head off when it's full grown. Yeah, that's what they said. And that's what they said in Jurassic Park, like oh, when the little things were hatching, you know, and all them people on the island.

Speaker 2:

Yeah.

Speaker 1:

No, uh-uh, laura Dern and all the people this is pre-Chris Pratt, uh-uh.

Speaker 2:

Yeah, but yeah, it says. The company seeking to bring back the woolly mammoth revealed it had produced three live dire wolf wolves puppies I didn't sound right. Remus, romulus and Khaleesi Is one of them named after Game of Thrones, I guess. So Whatever, we all know how that turned out if you watched it. I didn't watch it, but yeah, didn't turn out good Resurrecting a species that died out as many as 13,000 years ago, according to their calculations.

Speaker 1:

Yeah.

Speaker 2:

I don't know where that pops up. It was a really long time ago.

Speaker 1:

So the main goal is the woolly mammoth. Are we going for Ice Age here with Ray Romano? That's what we're headed for.

Speaker 2:

I feel like it's not a good time to bring back an animal that thrived in the Ice Age.

Speaker 1:

Yeah, just spitballing. Yeah, I'm just saying they're probably going to be terribly hot and uncomfortable.

Speaker 2:

That woolly mammoth is going to have a crew cut.

Speaker 1:

How did you lose all that weight? Well, I just started sweating it. How did you lose all that weight? Well, I just started sweating. It was like a sweat box in there. Oh my gosh, you look fantastic Wooly. Yeah, I know, I sweated all off. You know sweating to the oldies. Yeah, and so they have these pictures If you go online. Well, this is USA Today, but they have these cute little pictures. They're cute. Oh, they're super cute yeah.

Speaker 2:

Until they grow into stately adults and take over the world.

Speaker 1:

Right, yeah, how many are there? Three?

Speaker 2:

Three. It said they spent more than a year to decode the dire wolf's evolutionary history. Well, it used to be history.

Speaker 1:

Now it's just current events Said. We generated high quality ancient genomes from dire wolves that lived 13,000 and 72,000 years ago.

Speaker 2:

Which one is it? Yeah, high quality.

Speaker 1:

Yeah, what does that mean? No store brand 72,000 years ago.

Speaker 2:

Okay, if you say so. Yeah, but it says that dire wolves and gray wolves are much more closely related than previously thought. Well, they both have the word wolf in it. So I would assume they're kind of related. Yeah, yeah, I don't. I don't know how I feel about it.

Speaker 1:

I'm a little bit like okay, I'll give him this, ok, spectacular, you did that. You made that. It wasn't there for a long, long time. It had gone extinct and now it's back in existence. I will give you the. That's kind of amazing. And also quit messing, quit messing with it. Don't mess with that. Do you know how much we've already messed up, already, trying to do stuff with just stuff that already exists, uh-uh.

Speaker 2:

Yeah, well, it's like, and it says here, their findings also suggest the dire wolf goes back about 4.5 million years ago. Well, first of all, you said 13,000. You said 72,000.

Speaker 1:

Yeah.

Speaker 2:

And then four and a half million. Y'all don't know.

Speaker 1:

No, I don't know that. They did do the research.

Speaker 2:

This sounds like a fifth grader giving a report and he didn't go back and double check it.

Speaker 1:

Let's just clone eggs or like chicken eggs to eat, or iPhones so I don't have to buy another one.

Speaker 2:

Yeah, but so all right. So a gray wolf, like nowadays.

Speaker 1:

Yeah.

Speaker 2:

A gray wolf all right. Labrador retriever Right, 21 to 26 inches, 55 to 80 pounds. Okay and height 21, 26,. Okay, A gray wolf is 26 to 33 inches, about 50 to 150 pounds, and a dire wolf is 31 inches to 42 inches tall, 75 to 150 pounds. So it's almost. I mean, it's three and a half feet tall, 150 pounds, and it's a wolf. It's a wolf and we don't. I don't understand spending this much money and time. And energy On something we don't need.

Speaker 1:

No.

Speaker 2:

And or want. I don't think.

Speaker 1:

No, mm-mm, it is the houseboat of extinct animals. Nobody needs it, nobody.

Speaker 2:

Yeah, it says they had a vision of restoring the woolly mammoth. That would not only prove that a massive extinct animal can be brought back, but that the mammoth, if reinserted into the Arctic region, would improve the ecosystem and help combat global warming. Not sure if the woolly mammoth is going to recycle or I don't know.

Speaker 1:

I think it's going to die of being dehydrated.

Speaker 2:

Yeah, where are they going to put?

Speaker 1:

it, everything's melting anyway. Do they have a big like freezer?

Speaker 2:

Is there a zoo in the? Yeah, where are we?

Speaker 1:

Yeah, that's a good question. Is he doing an ice plunge every hour? What's happening? I don't know.

Speaker 2:

Yeah, I don happening, I don't know. Yeah, I don't get the whole yeah, so there's.

Speaker 1:

Where are these wolves? Where are they right now?

Speaker 2:

oh, does it say that is a good question. Oh, it says also, what about the unintended consequences?

Speaker 1:

yeah, what about? Oh, that's a section, isn't that nice? Somebody did do a little bit of somebody put.

Speaker 2:

We're messing with nature. I think you're doing more than messing with it. You've made wolves. Yeah, um, we're messing with nature. I think you're doing more than messing with it. You've made wolves yeah. We're genetically engineering these wolves, we know.

Speaker 1:

Yeah, you just told us.

Speaker 2:

Yeah, if we start tinkering with genes, there may be unexpected problems. Did that ever occur? No, I don't know. Maybe in like the first phase of research.

Speaker 1:

Yeah, like, what are the moral implications? Like, should we even be doing this? Um, yeah, so was it in the U S.

Speaker 2:

I'm going to have to.

Speaker 1:

I'm going to feel. I feel like it says yeah, I think it's in the U S, yeah, Um, I feel like it's this.

Speaker 2:

Yeah, I think it's in the US. Yeah, A lot of scientists have disagreed, which I'm. Yeah, I get it. Colossal used a gray wolf genome. Wait a minute. Okay, they used a gray wolf genome, which is 99.5% identical to the dire wolf genomes.

Speaker 1:

Hmm.

Speaker 2:

That don't even make no sense. So 0.5% is the different part.

Speaker 1:

I guess, and then is that what they made up?

Speaker 2:

And edited it to make it even more similar to the extinct dire wolf, altering their size. Y'all just yeah, uh-uh, y'all just willy-nilly.

Speaker 1:

That's.

Speaker 2:

You're just like going on a website to create a car.

Speaker 1:

Yeah.

Speaker 2:

And like can I do a custom color? You know, let's change it.

Speaker 1:

Yeah, let's do that.

Speaker 2:

That's what it is. It's like Jurassic Park, mm-hmm. Let's take a little bit of T-Rex A little bit. Mix it up with a little Velociraptor, the Endoraptor, or whatever.

Speaker 1:

Yeah, oh gosh, uh-uh. No, thank you, I don't know what I think.

Speaker 2:

I don't like it, but.

Speaker 1:

I don't like it.

Speaker 2:

I feel like it's a lot of wasted. Colossal Chief Sciences Officer Beth Shapiro. Wow, wait a minute. They're here with the image of the dodo bird, an extinct bird that Colossal has announced it hopes to bring back with its biotech and genetic technology.

Speaker 1:

They are the company from Jurassic Park.

Speaker 2:

These people need to be stopped immediately. You're going to bring back the dodo bird, which maybe it's just because I watched Ice Age or different movies or something. Isn't it like the dumbest bird in?

Speaker 1:

the world. It's called dodo.

Speaker 2:

It's extinct. It's called dodo and it's ugly as sin. It's not a pretty bird, you know. It looks like a fluffy flamingo put on a mask to go in and rob a bank. That's what it looks like looking at this picture.

Speaker 1:

Oh, my gosh man I the dodo bird. Oh y'all, both dodos, y'all need to stop making animals I just think oh, you know, I can just hear the music now from the movie, you know and like looking at the picture of these two scientists in front of the image of the dodo bird and suddenly like a t-Rex is running toward them, or velociraptors, and I'll say this the dodo bird in the picture that are standing in front of it doesn't look too happy that they're cloning. No, it's going to peck their eyes out. Yeah.

Speaker 2:

We're going to dodo this again. Yeah, things go extinct for a reason.

Speaker 1:

Yeah, come on, quit it.

Speaker 2:

Whether it be plastic straws in the ocean, whatever, I don't know, but yeah, yeah when something's gone, it's gone. It's gone. Yeah, you're not bringing back stuff.

Speaker 1:

No, that's weird. That's weird. It's already weird enough.

Speaker 2:

It. It's weird. It's already weird enough. It's weird. It's gross and y'all wasting money. Yeah, stop it. Stop making up jobs.

Speaker 1:

Yeah.

Speaker 2:

Stop making yourself feel good.

Speaker 1:

No.

Speaker 2:

You got some genomes from 75,000 years or whatever you want to say.

Speaker 1:

Yeah, sell them and put that money into schools. What you doing.

Speaker 2:

Yeah.

Speaker 1:

Buy some people food. It's like evil science.

Speaker 2:

It's just like some scientists that got too much money, yeah, and they're kind of bored.

Speaker 1:

Well, you know, at the beginning of Jurassic Park you'd like that little old man with the cane, with the ember and the amber.

Speaker 2:

That's all it is.

Speaker 1:

Yeah, and then by the end you wanted to just wring his neck Because you're like, you know what you did. Yeah.

Speaker 2:

Yeah.

Speaker 1:

Yeah, don't do it.

Speaker 2:

Well, I guess I'm glad they started with dire wolves instead of just jumping straight to woolly mammoth. I have a question, and this is more than a question. So when they clone, I guess they're cloning it, right? I'm going to feel dumb saying this out loud. So when they clone something so you're just coming it's just from thin air, right? So you've got to get all the genomes and all this stuff.

Speaker 2:

And then do you just inject that into a gray wolf and then, when that wolf has the baby, it's now the dire wolf, because you, is that how they do it.

Speaker 1:

So here's what A1, I mean ai says sorry I do like a1 steak sauce. I love it, sorry um. Cloning involves creating a genetically identical, identical copy of an organism. This is achieved through a process called somatic cell nuclear transfer, where the nucleus of a cell is transferred into an egg cell that has its own nucleus removed, the resulting egg now containing the donor's DNA is then stimulated to develop in an embryo which is then implanted to a surrogate mother. So maybe the gray wolf?

Speaker 2:

So they do all this Jurassic Park stuff, pop that into the gray wolf, and then that gray wolf gives birth to a dire wolf.

Speaker 1:

I don't know. I wish they had explained it. So I feel so dumb, so wish they had explained it.

Speaker 2:

So I feel so dumb so they're going to do this.

Speaker 1:

So if they do this, you're not the scientist.

Speaker 2:

Yeah, I'm not the one wasting my time on this, making up a job. So if they do all this, do they implant that into a regular elephant and then that elephant mom gives birth to a woolly mammoth. Mmm that elephant mom is going to be like what is going on.

Speaker 1:

Ow, I don't know. So colossal biosciences, these people. The de-extinction of the dire wolf involved the process of gene editing, not cloning in the traditional sense. I'm reading this, by the way, can you tell? They extracted DNA from the ancient dire wolf fossils. They compared it to the genome of the closest living relative, which is the gray wolf, found about 20 genes that contribute to the dire wolf's traits. Then these genes were edited into the cells of the gray wolves.

Speaker 2:

Okay.

Speaker 1:

And then the edited cells were used to create embryos which were then implanted into the surrogate domestic dog mothers. That's what it says.

Speaker 2:

Wow.

Speaker 1:

The resulting pups are essentially genetically modified gray wolves with some dire wolf treats.

Speaker 2:

Okay.

Speaker 1:

So maybe it's not exactly like the true dire wolf.

Speaker 2:

Yeah, maybe it's just like, when you say it like that, it sounds like they're still alive, like naturally.

Speaker 1:

Yeah, you know what I'm saying. Yeah, yeah, yeah.

Speaker 2:

Well, I was reading that about the woolly mammoth. So it says the goal is to create an elephant mammoth hybrid.

Speaker 1:

Okay, yeah.

Speaker 2:

Like a golf club. That's easier to hit.

Speaker 1:

I guess Not a true clone. As the mammoth's.

Speaker 2:

DNA is too degraded for full cloning.

Speaker 1:

But they did clone sheep.

Speaker 2:

Remember that? Yeah, when was that? Somewhere, that was like 10 years ago or something. They cloned a sheep, which is that like 3d printing, I don't even know how that works. You just hit the button and leave the room and come back I don't know this is getting too severance.

Speaker 1:

But, um, yeah, the birth of the dire wolves da, da, da, da-da-da-da, romulus, remus and Khaleesi, whatever are not cloned dire wolves, but rather genetically modified gray wolves that resemble dire wolves, okay, okay, so maybe it would be like an elephant with Snuffleupagus, and not Woolly Mammoth Snuffleup, you know what I mean? Like a little bit of a. It's a hybrid, it's a remix.

Speaker 2:

Well, romulus and Remus I know that sounded familiar were named after legendary founders of Rome, and Khaleesi is a reference to the Game of Thrones character.

Speaker 1:

Darnarius Targaryen. Okay, yeah, yeah, I didn't watch man, but I'm gonna put money on yeah anyway, I don't, yeah, I don't think there's to do it, but whatever I don't either if it makes you feel better yeah where does it stop, though, if they call?

Speaker 2:

if they start doing t-rexes, I'm out can't we solve the microplastics?

Speaker 1:

you can't, they said. Now you chew some gum, you're gonna get microplastics in your body. Can we get the plastic out of the extra first before we're doing this? You know what I mean. Can y'all make some really fine mesh like nets for the ocean or I don't know? Fix the ozone layer or something like that? I don't know. There's more pressing problems.

Speaker 2:

Yeah, do dodo birds eat plastic. Oh my gosh, you know, maybe clone that thing. Yeah, do dodo birds eat plastic.

Speaker 1:

Oh my gosh, you know, maybe clone that thing, yeah yeah, make some plastic-eating goats, I don't know. Just put them everywhere, put a little life preserver on them, just let them go to town.

Speaker 2:

Yeah.

Speaker 1:

I don't know.

Speaker 2:

Which I saw this on the news this morning.

Speaker 1:

Must be true. It's great news. It's great news.

Speaker 2:

It's great You've seen the thing about children's mattresses, which I don't know what a kid's mattress is, I mean is a mattress.

Speaker 1:

A mattress, what no?

Speaker 2:

it's like so it's the stuff that makes them flame retardant.

Speaker 1:

Yes, yes.

Speaker 2:

Whatever?

Speaker 1:

Causes cancer? Well, of course it's like a chemical Carcinogens.

Speaker 2:

And then when your kid's sleeping, you know their body temperature and all that Like they're breathing in like harmful fumes. Yeah, which I have a question Is my mattress just going to burst into flames or am I breathing the same thing Like adults don't sweat at night. They're talking about, like, well, kids' body temperature you know it can do this. I'm like.

Speaker 1:

I'm pretty sure we all. Yeah, that's why you got to wash your sheets, because it's gross. Yeah, yeah, everybody gets hot.

Speaker 2:

Yeah, that's why you got to wash your sheets, because it's gross, yeah yeah, I think a dire wolf could sleep on this and still be smelling it. You know, I don't know why they're just going after. I'm going to go out on a limb and say let's give it six months. There's some other recall or warning. Maybe that's what's on the tag when they say don't remove this tag.

Speaker 1:

Yes on the tag when they say don't remove this tag yes, under any circumstances. We told you like ever even after I buy it even after.

Speaker 2:

Yeah, but yeah, that was this morning no, I've not heard that.

Speaker 1:

Yeah, but they make that. They make kids pajamas like that I guess. Well, I guess pajamas you're wearing it but it's right by your skin, not bad't that bad too, yeah, which I feel dumb about that.

Speaker 2:

Everything is a little bad. How close are we getting to fires?

Speaker 1:

And how does the chemical stay in it after you wash it that many times?

Speaker 2:

And don't call it that. That makes it sound like you could just walk through the fire.

Speaker 1:

Yeah, yeah, uh-uh what are firemen wearing? Yeah, that's flame retardant.

Speaker 2:

They're going in burning buildings. Were people just bursting into flames 300 years ago, Like just everywhere.

Speaker 1:

Maybe they could use those mattresses to get people out of the buildings. Like you know, make one of those slides or ramp or something. Seriously.

Speaker 2:

Well, that's what they do when like grab a mattress.

Speaker 1:

Right, yeah, yeah, yeah and run through it. Well, maybe that's why you gotta jump out of the building.

Speaker 2:

Yeah, I ain't jumping on that thing. It's hot, there's fumes all over it. Go get that dire wolf. Come up here and get me. I'm going to hop on this dodo bird and fly down. Which now I'm thinking, could they fly? I don't think they could.

Speaker 1:

I don't know. I know a woolly mammoth ain't probably moving very fast. Do you think they move fast Did?

Speaker 2:

they? I hope not.

Speaker 1:

Yeah, herds of woolly mammoths.

Speaker 2:

Well, now I feel dumb because a dodo bird is a flightless bird. That's an ugly bird number one.

Speaker 1:

You know what? Okay, I thought that the image that the scientists were standing in front of we just looked this up on the Internet y'all Picture of a dodo. Look it up at your leisure. I thought it was just sort of an outline with no color.

Speaker 2:

Oh, okay. On it but that's how it looks. Yeah, there, that's terrifying.

Speaker 1:

That's a little scary looking, yeah, why you gotta If you go clone something.

Speaker 2:

It's pretty hummingbird or something.

Speaker 1:

I'm just saying Miss.

Speaker 2:

Yeah, I'm trying to see why they went extinct Primarily due to human activity. Oh, let's bring them back now. We ain't got none of that going on. And the introduction of invasive species I butchered that. Y'all know what I meant Like pigs, rats and cats. I'm going to go out on a limb and tell you something In 2025, you know what we have? We have pigs, we have rats and we have cats, mm-hmm.

Speaker 1:

Yeah.

Speaker 2:

And apparently direwolves and y'all going to bring back dodo birds.

Speaker 1:

Let's let these kind of roam around and not know what they're doing, so they can go extinct again.

Speaker 2:

Oh, we just brought them back and they're gone again and they're gone.

Speaker 1:

Yeah, no, that's silly.

Speaker 2:

I think, whatever it is I watched maybe it was like Madagascar or whatever the dodo birds like just were dodos and just ran off a cliff, which.

Speaker 1:

Oh yeah.

Speaker 2:

They kind of look like they would do that.

Speaker 1:

Yeah, they do. They are not the scientists of birds, for sure. Well, they didn't ask us. But I do. I don't believe in the bringing the extinct things back, I don't either.

Speaker 2:

I did just click on this, sorry. It says why was the dodo called a dumb bird? They weren't dumb, that's what it says. Somebody had an affinity for dodo birds. They weren't dumb, they were trusting.

Speaker 1:

Aw Were they.

Speaker 2:

Did they? Tell you that Because you're a dodo. It said they had no reason to fear man, as they'd never seen a human. Okay, okay, well, how would you? Yeah, I don't know who wrote this did. The dodo said when humans began to hunt them. They had a. They had few defenses, being flightless, that didn't help a lot did it, and not especially fleet of foot. Oh my god I think I know why they went extinct yeah right there's like a walking target with feathers y'all want to go dodo bird hunting.

Speaker 1:

It's dodo season, you don't even need camouflage, you just walk right up. It's going to be over pretty quick, and then we'll just hit Wendy's on the way back. That's what I'm thinking.

Speaker 2:

Yeah.

Speaker 1:

There's no, you don't need a four-wheeler.

Speaker 2:

You don't need a dodo.

Speaker 1:

You probably don't need a cooler. You probably don't need a gun. You could just clock them in the head, sounds like.

Speaker 2:

Yeah, they're very trusting. You don't even need a Dodo call you, just go come here, Dodo.

Speaker 1:

Yeah.

Speaker 2:

And you hit them with a, put them in a bag. Hit them with a bat.

Speaker 1:

I don't know. The next one looks at you. This is violent. We just got dark, but yeah, it's okay. Good gracious Anyway, oh Dodo.

Speaker 2:

Well, I don't know, I don't think we should clone anything.

Speaker 1:

No, that's what museums are for, yeah what's going to happen to museums?

Speaker 2:

You're going to bring back all this stuff and take down the woolly mammoth display outside.

Speaker 1:

Yeah, right what you're going to have a skeleton.

Speaker 2:

I didn't think about that, I'm offended.

Speaker 1:

You can't lay them to rest properly. Somebody's been working on a dodo bird display. Oh yeah, at Smithsonian they're like what?

Speaker 2:

There's some place in Brazil. It's like we got a whole museum for dodo birds yeah. You know they're back right. What yeah?

Speaker 1:

Take it all down. Take it all back down, shut it down.

Speaker 2:

Let's do dire wolves. I hate to tell you.

Speaker 1:

I saw them on the way here.

Speaker 2:

And before you get some new blueprints, they took the Willie Manless coming back. So just keep going. Just set up a museum for something we have now that is about to go extinct Polar bears.

Speaker 1:

Yeah, let's do something like that.

Speaker 2:

Because they ain't going to bring them back for a while. We've seen that Nobody wants to see the band that broke up three years ago come back on tour.

Speaker 1:

No, but 40 years ago. People are like, oh, I'm going, they're still buying tickets to that. They don't care how old they are.

Speaker 2:

Anyway, well.

Speaker 1:

Watch out for the wolves, I guess, I don't know.

Speaker 2:

Yeah, if you hear howling? Yeah, yeah go in the house.

Speaker 1:

Go in the house.

Speaker 2:

Anyway, that's all I got.

Speaker 1:

All right.

Speaker 2:

Have a good one.

Podcasts we love

Check out these other fine podcasts recommended by us, not an algorithm.

The Nateland Podcast Artwork

The Nateland Podcast

Audioboom Studios