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BlueDot Narrated
Audio versions of the core readings, blog posts, and papers from BlueDot courses.
BlueDot Narrated
Scaling US Pathogen Detection
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BlueDot Impact
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Audio versions of blogs and papers from BlueDot courses.
Description: This post models how an effective biosurveillance system might work in the US using metagenomic sequencing (MGS). Metagenomic sequencing can read out any nucleic acid (RNA or DNA) in a sample. Analyzing these fragments allows the identification of both known pathogens as well as unknown reads that could represent a new threat.
Original Text: https://naobservatory.org/blog/biothreat_radar/
Author(s): Simon Grimm, Lennart Justen, and Jeff Kaufman.
A podcast by BlueDot Impact.
Summary
Structure and cost of an advanced biosurveillance system
Overall structure
Overall cost
Collection
Processing
Analysis and threat detection
Pathogen detection performance
Monitoring
Discovery
Features needed for optimal performance
Conclusion