DDI of the Month Podcast
Presented by Global DDI Solutions in collaboration with Academic Medical Education, the DDI of the Month podcast brings you the latest updates on drug-drug interactions.
Each month, a new paper will be selected and the author invited to discuss their findings and explore how this can optimize DDI management and patient care going forward.
Host: Dr. David Burger - Professor of Clinical Pharmacy at the Radboud University in Nijmegen, the Netherlands.
He is an Executive Editor of BJCP and serves on the editorial boards of TDM, JAIDS, JAC, and Antiviral Therapy. Since 1997 he has been leading a research group focussing on clinical pharmacology of antimicrobial agents with emphasis on HIV, TB, fungal infections, and hepatitis.
DDI of the Month Podcast
Episode 6: The Role of P-gp and the Impact on Clinical Outcomes | Leonie Bogaard
In this episode of the DDI of the Month podcast, Dr. David Burger dives into a critical topic: P-glycoprotein (P-gp)-mediated Drug-Drug Interactions with Dr. Leonie Bogaard. Join us as we explore the role of P-gp, a key transporter involved in drug absorption and elimination, and its impact on clinical outcomes.
In this episode, we discuss:
• How P-gp modulation affects systemic drug exposure.
• The challenges in managing DDIs due to overlap with enzymes like CYP3A4.
• Practical recommendations for identifying and addressing P-gp-related DDIs in clinical settings.
Don’t miss this engaging discussion, featuring insights from recent research and expert recommendations on improving patient care while minimizing risks.