The Jenes Pod
I'm Damien Hsieh, a Year 10 student from Hong Kong who loves genetics and molecular biology. These molecules and proteins are practically invisible to the naked eye, but when closely examined, can reveal the inner complexities of thousands of millions of processes that make you. With this science now being harnessed for good, this genetic technology of the future (and practically now!) is what I will be discussing in Jenes, and I hope you will enjoy the breakdowns and explanations of the complex human genome.
The Jenes Pod
Episode 4 - Genetics, The World's First Butterfly Effect
We've all heard about the butterfly effect, a small action causing a big consequence. But how about the butterfly effect in the context of the human body? Well, at the Jenes Pod, of course, I'm going to link it to genetics, with the prime suspect of the butterfly effect coming from a phenomenon called the single nucleotide polymorphism or SNP. So yes that's what we're going to be talking about today, get ready to see how one change in your genetic code can manifest in such a massive difference which can be extremely helpful for us to know.
Works Cited
APS. “Circa January 1961: Lorenz and the Butterfly Effect.” Aps.org, www.aps.org/archives/publications/apsnews/200301/history.cfm. Accessed 28 Dec. 2024.
Armitage, Rebecca. “For 40 Years, Police Hunted the Golden State Killer. A Discarded Tissue Brought Him Down.” Www.abc.net.au, 21 Aug. 2020, www.abc.net.au/news/2020-08-22/the-forty-year-hunt-for-the-golden-state-killer/12579638. Accessed 28 Dec. 2024.
Li, Yun, et al. “Single Nucleotide Polymorphism (SNP) Detection and Genotype Calling from Massively Parallel Sequencing (MPS) Data.” Statistics in Biosciences, vol. 5, no. 1, June 2012, pp. 3–25, https://doi.org/10.1007/s12561-012-9067-4. Accessed 28 Dec. 2024.
NHS England. “Personalised Medicine.” England.nhs.uk, NHS, 2019, www.england.nhs.uk/healthcare-science/personalisedmedicine/. Accessed 28 Dec. 2024.
Novroski, Nicole M. M., and Jennifer C. Cihlar. “Evolution of Single‐Nucleotide Polymorphism Use in Forensic Genetics.” WIREs Forensic Science, vol. 4, no. 6, May 2022, https://doi.org/10.1002/wfs2.1459.
Ray, Balmiki, et al. “CYP2D6 Haplotypes with Enhancer Single-Nucleotide Polymorphism Rs5758550 and Rs16947 (*2 Allele).” Pharmacogenetics and Genomics, vol. 29, no. 2, Feb. 2019, pp. 39–47, https://doi.org/10.1097/fpc.0000000000000363. Accessed 28 Dec. 2024.
Saey, Tina. “New Genetic Sleuthing Tools Helped Track down the Golden State Killer Suspect.” Science News, 29 Apr. 2018, www.sciencenews.org/article/golden-state-killer-suspect-dna-genetics-genealogy. Accessed 28 Dec. 2024.