Fill Me In: An Aesthetics Podcast
On Fill Me In: An Aesthetics Podcast, Jon LeSuer NP-C and Nicole Bauer FNP-BC dive deep in the world of aesthetics. As aesthetic nurse practitioners with their own medical practices, Jon and Nicole fill you in on everything in their field.
Fill Me In: An Aesthetics Podcast
All About PDGF (Platelet-Derived Growth Factor) | Episode 34
In this episode of Fill Me In, Jon and Nicole dive into the latest hot topic in aesthetics: Platelet Derived Growth Factor (PDGF). They discuss the effectiveness of PDGF in enhancing various treatments, from microneedling to under-eye and hair restoration injections. They explain their techniques for administering PDGF, the benefits compared to PRP, and the importance of reconstitution with bacteriostatic saline. With insights from their experiences and emerging protocols, they shed light on the potential of PDGF to revolutionize the aesthetics industry.
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***DISCLAIMER***
The content of this episode of Fill Me In: An Aesthetics Podcast is intended for educational and informational purposes only and does not constitute medical advice. While PDGF (Platelet-Derived Growth Factor) is FDA-approved for certain topical applications, it is not approved by the FDA for injectable use. Any discussion of injectable PDGF reflects off-label use, which carries potential risks and should only be considered under the guidance of a licensed and qualified medical professional.
The hosts, guests, and producers of this podcast do not endorse or recommend the off-label use of any medical product without proper clinical training, patient assessment, and full informed consent. Listeners are strongly advised to consult with their healthcare providers and adhere to all applicable laws and regulatory guidelines. We expressly disclaim any and all liability for any outcomes related to the use or misuse of the information presented in this episode.
PDGF Resources:
Lynch Regenerative Medicine: https://www.lynchregen.com/
Waseem Garbia PA-C | https://www.instagram.com/unfilteredinjector/ | https://www.patreon.com/user?u=79797191
Erika Barry NP-C | https://www.instagram.com/injectorbunny/ | patreon.com/Botoxbunny1
Olivia Salmen FNP-BC CPSN | https://www.instagram.com/oliviasalmen_aesthetics/
On Fill Me In: An Aesthetics Podcast, Jon LeSuer NP-C and Nicole Bauer FNP-BC dive deep in the world of aesthetics. As aesthetic nurse practitioners with their own medical practices, Jon and Nicole fill you in on everything in their field.
Fill Me In is hosted by Jonathan LeSuer, MSN, NP-C, and Nicole Bauer, MSN, APRN, FNP-BC.
Follow Fill Me In on Instagram!
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Follow Nicole on Instagram:
https://www.instagram.com/aestheticnursenicole/
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https://www.instagram.com/injectorjon/
Exhibit Medical Aesthetics website:
https://exhibitmedicalaesthetics.com/
Tox and Pout Aesthetics website:
https://toxandpout.com/
Producer of Fill Me In: Joseph Ginexi
Alright guys, welcome to another episode of the Fill Me In podcast. I'm injector John
and I'm aesthetic nurse to Cole.
It's been a minute, Nicole.
It has. It has, and I'm very excited for today's episode because we're gonna be, it's talking about the new hot topic again.
It's all about growth factor people.
It is all about growth factor. It is especially platelet derived growth factor.
Mm-hmm. And as everything we're seeing Yeah. On Instagram, you just got it. You're practic, right? I did. I did. Yeah. So we, so exciting. We decided to bring it on like a couple weeks ago, but we just got like, you know, our training and mm-hmm.
And really feel comfortable with it. So we just launched it to patients and we literally sold out of it in one day.
I mean, crazy.
Yeah, yeah, yeah. So we all treated each other too, so. As you guys can see.
Yep. She's a little bruised.
Look at a little bruise. Little swollen. I'm definitely a And what technique did you do
though?
Definitely a little tender.
So yeah. So we did needle on bone needle. Yeah. And because we're still. Kind of getting acclimated with the product. We did backfill BD syringes with it too, so that it was a little bit more of a smaller needle. Um, you can just take what they give you and put like a 30 gauge needle on it.
Mm-hmm. Um, but we preferred, especially in the under eye, to just fill separate BD syringes. So it's a 32 gauge needle and you're using a new one each time.
Right.
Um. Everyone, we injected four people. The other three people are not bruised.
Mm-hmm. Oh, I mean, it's
just me.
The luck of the draw, you know? Yeah.
Yeah. But I, I tend to bruise pretty easily. But I will tell you I am pretty tender, which I think is to be expected because of the fact of the histamine response and the tissue response and fibroblastic, fibroblasts and all that, so,
yep.
But, um, mm-hmm. I do think the needle probably does play a little bit more of a role in that tenderness as well.
Yeah. Because tell the people what you typically do. You usually use cannula, right?
Yeah. Um, I feel like I just wanna preface this, like mm-hmm. I, I've gotten, I don't think the amount of dms about PDGF is just unreal. Like, yeah. Protocols, what do I do? Mm-hmm. How do I dilute it? Mm-hmm. So we're gonna go over like all of that and like what we do, um, in our practices.
Um, but I personally use a 25 gauge, one and a half cannula. When I do PDGF. Um, I reconstitute. PG F bb, um, with 1.5 ccs of bacterial static saline. Um, so it yields two ccs of product so that it, then it's one cc per eye. And then I use a 25 gauge cannula, right? I make the poke, literally wait, right where you would do tear, trough, um, filler.
Uh, and I go to periosteum, so I'm deep. So you wanna make sure with this product, you're deep.
I was gonna say a good point. Like if you're not comfortable with cannula use, you should not be using cannula with this product because you do not want it in that, in the superficial plains, you wanna it deep and down on bone.
Mm-hmm. So if you're not comfortable with cannula use, I think needle is definitely,
and honestly this is coming from someone who, when I first got the product, it was, it's obviously, as we all know, FDA approved for topical use. Right. Um, now P pgf BB is. Is approved for injection for other areas on the body, just not the face.
Mm-hmm. Um, but so now we're injecting it off label, like we do a lot of things in the face, but mixing it with bacteria, static saline. When you get PDGF, you get it. We get it from a company called RE Essence, which is, um, where the majority of people are getting this product from. Um, it's owned by Lynch, Lynch Regenerative medicine.
Um, we could even probably even put them. Yeah. On here. So people listening, if you're interested in this product, you can reach out to them. Mm-hmm. And they can find a local rep to hook you up and send you samples and to try it out and learn more information. Um, but you're not using the. HA serum that's in the res package that it comes in.
You're only using that serum and combining it with the PDGF when you're using it topically. Right.
So like I had microneedling done two weeks ago with it, which by the way, absolutely obsessed with, oh, like I, to be completely honest with you, I wasn't expecting anything like crazy. You know, I've worked with growth factors before.
Mm-hmm. I, I've, I've had exosomes at my old practice like. I was not expecting to be that impressed, like my skin looks like glass and within like two to three days, like the healing was so much different than with my own PRP or exosomes that I've done in the past. So I was like shocked. That's when I was like right away.
I'm like, buy it. We need it.
No, that literally it's the glass skin. Mm-hmm. Like you don't understand until you do it. And of course, like of course you, Nicole, you've been doing these treatments for years, so like maybe someone who's never had this treatment, you might not have that appearance after one.
Right. Um, it's, it really does yield better results than just doing microneedling alone, and it's different than PRP. It's with PRP, it's a wonderful treatment, right? We still obviously offer it to patients that wanna use their own blood and use their own growth factors, but with. PRP, there's more variability.
Mm-hmm. With PDGF, you're getting up to 300,000 times more growth factor concentration.
Right. So
you're guaranteed more consistent results with it.
And for patients listening that that's because basically other factors, uh, you know mm-hmm. Social, like your lifestyle, hereditary, like all these things kind of play a role in your PRP components.
Right. So it's, it's just like, even if you drank the night before, like your PRP can be not as mm-hmm. Potent as it, as it. Could be so, and we can't
test it in the office.
Mm-hmm. Right. We won't know. Yep. Exactly. Mm-hmm. And also age. Age plays a huge role. Mm-hmm. You know, like my PP is gonna be very different than a 60 or 70-year-old woman.
So it's just that now you can kind of take that guesswork out and use something like PDGF that's gonna. Give them as much potency, if not more.
Yeah. It's just so crazy. Like you're looking at this little baby syringe of PDGF, that's 0.5 ccs, and you're like, you're not gonna do anything. And then with one treatment, then you do it, whether it's injecting it or you know, putting it topically and you're like, oh, okay.
It did something.
It really did something. It did a lot.
It's a lot. But
she's really potent. Yes. Right. Yep.
Yep. Mm-hmm. So how you were explaining that you mix with the 1.5, so we. Had done it on ourselves with actually a one cc dilution of mm-hmm. Bacteria, static saline. Um, so it was a little bit more concentrated, and I do think that's why I'm a little bit more tender as well.
Sure. Um, and I think too, like on this one eye, if I can show you guys, you can kind of see the, um, angiogenesis, oh, I don't know if it's gonna pick up on the camera, but like right through here, it's a little bit of like redness and some mm-hmm. Little capillaries too, so, mm-hmm. It basically works. We place it down on periosteum because that's where those fiberglass.
Are sitting. Um, and it, it basically. Creates more fibroblasts, stimulates those fibroblasts so you can have more collagen and elastin. Um, and in the meantime it also is making more vessels and things like that. And that's why you see that angiogenesis or that that redness in the area. And that's also why you have all the swelling.
Yeah. I remember when I was experimenting with it, you know, I was like, oh, I'm just gonna inject it kind of like I would do PRP or I'll do it a little bit more superficial and mm-hmm. So I. Had my RN injected superficially using a cannula on me, and oh boy did I have my angiogenesis. And, and honestly, I, I wanna show you guys the picture because Yeah.
We
have to put it in.
Yeah. And we'll put it in up here. But, um, I of course knew that this was part of the process. Mm-hmm. And, you know, it really just started, it started the next day and it lasted for probably, I would say about a week, maybe up to 10 days, but like the worst. The worst part of it was like the first, like day two to day five.
Yeah.
Um, and then I had a little bit of swelling, like little malar edema, um, probably on day four, day five. And then it quickly resolved by day seven to 10.
Yep. And I remember we, I think we filmed like. In between that. I think we did. Yeah. And you were like, what do you think? Do you think it's gonna come down?
I'm like, I know. Oh my God.
I was like, oh my God.
Because it's like that, you know, that like panic moment, but, well,
and I'm white, Caucasian, French, like, and I'm very reactive. So you're like me for me. Yep. Yeah, exactly. We get rich red. It's just like me.
Yep. Mm-hmm. So, yeah, and, and two, I think it's, it was kind of still very new then.
Yeah. So techniques weren't really. Quite no, because it's, it's not new in the fact of like, it's not a new creation, but it's new in the aesthetic world. So they've been using it for diabetic ulcers. Um. Orthopedic surgeries. Mm-hmm. Even orthodontics, I think. Right? Like in the mouth. Yeah. Or macular surgery to augment
bone.
Yes. Yep. Mm-hmm. So there's a lot of uses. We're just now using it off-label in our setting. Mm-hmm. Mm-hmm. For aesthetics. Mm-hmm.
Yeah. And not only are, are we. Injecting it under the eyes. I'm, I'm injecting it in the smile lines. So nasal labial folds, I'm injecting it into the accordion lines. Uh, we're injecting it into the hair to stimulate hair growth, which is incredible.
Um, so we'll go through all of that. Yeah. I, I use the same reconstitution for all of them with, for, well, for under. As, as I do, smile lines and also accordion lines.
Okay.
Um, there's sometimes I'll do like up to two ml, like if I just want a little bit more spread. Mm-hmm. Um, but normally I'm using just that 1.5 cc recon for the scalp.
I do tend to, I use two syringes of P DG fbb, and I reconstitute it with four ccs of bacteria, static saline. So that way I'm yielding five ccs of product.
Okay.
Because honestly, like when I'm doing, when we're doing PRP for hair mm-hmm. Like, I love to get at least eight or nine ccs of PRP for people.
Mm-hmm. You know what I mean? And that way you can spread it everywhere. Um, so I like to have as much product as possible, especially when treating the hair
right. No, absolutely. I'm just pulling up my protocols.
Yeah.
Uh, where are they?
But yeah, just a big, I think the biggest takeaway from this is to make sure, 'cause I actually just was talking to another colleague in the industry about PDGF and she was bringing it onto her practice and, um, she had thought that.
You know, we were mixing the uncross link hyaluronic acid serum that comes with it. With it and injecting it under the eye, which not is a no-no. Mm-hmm. So we wanna make sure if you're injecting it under the eye or smile lines, accordion lines, the hair, make sure you're using bacteria static saline. The only time you're using that, that serum that it comes with is when you're.
Using it topically, topically,
so after lasers or microneedling, but you never want that ha in it if you're gonna be injecting. Yep. Yeah. So for hair, same thing. 1.5 cc of the bacteria, static saline, and then the 0.5 of the PDGF. Um, and then two of those. Yeah. Yeah. And then depending, I guess on the, if, if it's a.
Large, large area, you might need more.
Yeah. Like I have this guy that went to Turkey. Mm-hmm. And he got a hair transplant and he came back and it was like the cap of his head. Mm-hmm. So I ended up doing four ccs and I just, I just wanted it to really just go all around. Get around in there. Yeah. We used two.
Mm-hmm.
This is a great option for people that have had Oh, hair transplants like it is. Mm-hmm. Suggested to get this after, and you may have even been told to do PRP, but this is something that's just so much more potent and predictable. So, and that's exactly what I told that
patient. Mm-hmm. I, you know, he came in for PRP and I said we can totally do PRP.
Mm-hmm. But it is a little bit more variable. And I am, I, there's no way to know how much growth factor you have, but if we do PDGF, it's guaranteed and more.
Right. And I think too, you know. With growth factors, there was quite a lot of buzz about, um, other ones and exosomes and PDRN and mm-hmm. With PDGF, it's.
It's made, it's lab created. Yeah. And it, it is sterile. And I think that's a huge component to this. There's no human component.
It's actually more sterile than your own blood. Mm-hmm.
Right, right. And exactly. So when we do your PRP in the office, of course we're using aseptic technique and we're cleaning you with alcohol and stuff.
But you, we are kind of drawing that up in open air and, you know, it's not, it's not technically fully sterile like this would be. So this, this actually is very, very safe compared to mm-hmm. Um, other ones that may have had a little bit more of controversy in the past.
Yeah. Yep.
Um, yeah, so we're gonna play around with the 1.5 bacterial stomach saline.
'cause we did do it with the one, so, yeah. Uh, I think, and
you're gonna have a great result. Yeah. And I think too, you're just gonna have a little bit more soreness. Exactly. I think just because it's more, um, concentrated.
Yeah. Concentrated. Yeah. Mm-hmm. And I think too, with that 1.5, you just, you do get a little bit more out of it where you could put a little bit more, you do other areas when you're treating the laugh line and the.
Radio lines. Are you still deep or are you a little bit more superficial there?
I'm a little bit more superficial.
Mm-hmm.
Um, and I just let them know they could have some angiogenesis, which is normal. We love it. It's new blood vessels, you know, forming, which is great, which means new skin tissue, new regeneration.
So, um, it's still worth it.
Yeah. I think that. No, I think explaining that too, the redness and stuff is to be expected because with filler you don't really, you swell, but you don't see that. So sometimes it might be alarming for some people. Yeah.
And I'm not gonna lie, there's some patients that I, I use, I, I, I call it the sandwich method.
Mm-hmm. So like, I like to inject deep.
Mm-hmm.
And I'll do the majority of it deep. But for some of those patients that come in and they have that really cre skin and that loose skin, I really. I, I, I wanna hit that skin. Yeah. So like, I like to come back and go a little bit more superficial, not too superficial, where you're seeing the gray of the cannula, but just enough so that way you know, you're also touching that part as well.
Mm-hmm. Does that make sense?
Absolutely. Absolutely. I don't
know, like, and I just tell them multiple, you're gonna have redness expect it. Right. It'll go down where concealer will be good result. Yeah. Whereas when you're
placing it deeper, you might not, sometimes you might not even see that angiogenesis might, if you're really, really deep, you know, you'll just feel that kind of.
Tenderness, but some people don't even get as tender as others, you know? Mm-hmm. So it really just depends on the person. Here's a stat that should make you pause. Nearly one in five med spas open today, launched in just the last year alone. The competition is real, but so is the opportunity in front of you.
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Hey guys, just popping in. If you're enjoying our podcast, please subscribe and don't forget to follow us on Instagram injector John and aesthetic nurse call.
Yeah. I actually, I, a lot of people are saying, oh my God, like one of my coworkers said, is this gonna replace under eye filler altogether? And I'm like, no, no, no. It won't replace it. Filler
still has its place. Exactly. It still has its
place. Mm-hmm. It's just so nice to have a treatment that's not filler for the under eye, because there's so many patients that aren't candidates for under eye filler.
Right.
And that, that actually brings up a great point. So. With this product, with people that do have a lot of under eye bags or like a lot of under eye swelling, fluid retention. Yeah. This is still something that you probably do wanna avoid. Mm-hmm. Um, because it's, it's still causing collagen and elastin and Oh yeah.
And you don't, you don't wanna, you don't wanna add more bulk to that area, especially if they're already dealing with fluid retention and swelling and on and off and things like that. Um, especially with like fat herniation, so they have a lot of that fat herniation there just. Caution. You know, you don't, they're still the best candidate for a blepharoplasty, you know?
Yeah. Um, you still have to be careful with that. So it's not, it's not like this one size fits all. It's still, there's still people that aren't gonna be the best candidates for it. So people that have like that intense fe festing and things like that, this can cause more fluid retention.
It is so weird though, Nicole, because there's some patients though that even though they've had some intense festing mm-hmm.
I've decided to do it
and they've been fine and some,
some people it actually improved it.
Really interesting. I, so I don't, I guess the thought would be right, the angiogenesis would be, 'cause it's creating more vessels. You're thinking that you're creating more fluid retention because you have more vessels, but maybe because you're creating more vessels, you're helping that fluid actually Yeah.
Move out of the area. You know? I guess there is two sides to that.
Yeah. And. I, I know. And I'm like, I had to think like, if this is regenerating everything but nerves, maybe it's just regenerating, it's giving more strength to the tendons, the ligaments of the eye, the muscle around the eye, the skin. So it's actually contracting and moving that lymphatic fluid better.
Right, right. I don't know, like I'm just thinking outside the box.
Well, right, right. And I, I think too, there's a lot that we'll learn. I so too, now that there's so many more people using it in the aesthetic world, like there in, in six months, who knows? Maybe we'll be like, oh, that was, that's an old thought.
You can use it in anyone, you know?
Right. Like I, um, there, I, I actually wanna show this before and after. Mm-hmm. Like, I'll have Joey, but like this patient. Yeah.
Oh, incredible.
Yeah. Her before and after. See,
I think people that have a, a decent hollowing, even though she has a little bit of that fat pad, like I think she definitely is a good candidate.
Well, and I don't know if you can tell, like she had a lot of anterior medial cheek loss. Mm-hmm. Like volume loss. So we ended up doing obviously Voluma Yeah. To bone here, um, to give that anterior cheek support and the ligament support the under eye. And then we did two sessions of PGS space eight weeks apart.
That's
incredible.
Then she just did her third. So this was right before I injected her for her third treatment. Wow. And she wasn't a candidate for under eye filler, at least in my opinion, because her skin, like, it was like skin bone. That's how hollow she was. Mm-hmm. Like she had nothing there. And I felt like if I did any under eye filler, it would almost be wormy and it just would not look right.
Yep. Absolutely. You would. You would see it and she would have kindling.
Yeah.
Yeah, yeah. Yep. Yep. So I think. Someone like her is like the optimal
Yes. Yeah. And I actually had someone that I've done voluma to the cheeks mm-hmm. To the, an medial cheeks. I've done volbella twice to the under eyes. Everything's been great.
She came, um, for her neurotoxin and another touchup if she needed it. And I was like, no, you're, you're good.
Yeah. Like,
you're actually good. And I was like, I don't think I need to do filler. Let's do PDGF. Mm-hmm. We ended up doing PDGF
incredible.
It like. It, it was just beautiful. Yeah. Like it got, it ended up filling in areas that you can't touch with.
Filler too. Like does it improve your skin, I think too. Right.
And you know when, when you think about this, it's very liquidy. So it spreads very easily. Yes. So you can give it a nice massage after and you're, you're gonna get that whole area rather as with filler. It's really where you're placing it.
I know.
That's a good point too, actually. I'm glad you brought that up. So someone that has a lot of filler or like, you know, we see a lot of times. In our practices, like patients that maybe got under eye filler years ago and, and they're almost overfilled.
Yeah.
Um, if someone like that comes in wanting, I just had one today.
Yeah. You have to dissolve some of that filler before you put this in there. I had a
patient today where it was a plastic surgeon who treated this patient knowing that she had under eye bags, treated them. With filler and she had tyle.
Yep.
And, um, she was, ended up being in with PDGF under eye and I just, I ended up not doing it.
I ended up doing, suggesting dissolve and maybe getting a lower bluff. Mm-hmm. Yep. Um, so that's another thing. It's really important with your patients during a consultation to know when to refer out for surgery. That's another thing too. Yes. Obviously if they don't want it, then you just, you know, could talk them through it.
But, um. This lady's gonna need this dissolved if she ever gets like a lower bluff or in the future. She didn't want it, but it's okay.
Yeah, it's okay. That's what we're here for. It's okay. Exactly. Yeah. That's, and, and too, I, that's actually a little off topic, but. Explaining to them like, listen, you're how long you've had this filler?
Five, 10 years? Mm-hmm. Like you're used to seeing yourself it four this way. It was four years. Yeah, it was four years. And she
still had the under eye filler. I mean, under eye filler. Lasts a really long time.
Oh yeah. Up to like probably up to 15 years, don't you think? Oh, yeah. Mm-hmm. But dissolving that is like.
They're not gonna see themselves the same because, you know, they might be puffy now, but when you take that away, I feel like almost they might feel like they look older because that hollows back even more hollow.
Yep, yep. And you, it's also kind of breaking down some of your own mm-hmm. Collagen, right.
And ha so like, yeah. Yeah.
It, it typically will, I feel like your own ha typically replaces fairly quickly, you know? Okay. But that area is, is so thin that, and with the amount of under eye filler mm-hmm. Where it ends up. It's hard to, to, to pinpoint.
I get a lot of questions from people asking, can you do sculpture and PDGF in the same day?
The answer is a hundred percent yes. Mm-hmm. Yep. I, I do PDGF under eye and I do sculpture face all day every day. Mm-hmm. It is beautiful. So like the ultimate biosim treatment, um, I feel like patients. Look so lifted and so refreshed after It's insane. Yeah. Um, I'll do PDGF and filler in the same visit. Um, I've injected skin ViiV mixed with PDGF.
I will say the combination of those two, you do have a little bit more swelling. Mm-hmm. Um, during those where the, where you injected those little aliquots of skin v when you mix it with PDGF. Mm-hmm. Just because of that fibroblast activity. Um, so it definitely con, you know, advise your patient. Yeah. It's normal to have some of that for about up to three weeks.
Mm-hmm. And then it finally settles.
Okay. That's something that we'll talk about in the next episode is kind of mixing PDGF with, with other things like radius and stuff like that. Yeah. So stay tuned for that one, guys.
Oh, we're not talking about it now.
Oh yeah, you're fine.
Yeah. I'm
kidding. I just did on, um, Tara, our manager, we did sculpture right after her PDGF too.
Oh, perfect. We love it. Yeah. Yeah,
yeah.
That's something new that we've been, we're loving sculpture. It's like,
it's so good. Yeah. It's, it's nice. It's, yeah.
It just gives a nice glow and, and in areas where like, you know, maybe someone's not open to filler and they want something mm-hmm. That's gonna stimulate their own collagen.
It's a great option.
It is. And it's, it's great. Especially there's some patients that almost need their skin primed before mm-hmm. Doing filler so that way they can handle it the filler. Mm-hmm. So true. That's where sculpture comes into play.
Yep. So true. Mm-hmm. So the biggest question on the table that everyone always asks about is the vascular occlusion risk with the PDGF.
And,
and it is not a concern. The, um, halflife of the product is two and a half minutes. So the only area that it is a concern is the supra artery. Mm-hmm. Um, so you wanna be careful in that area. So you can inject in the glabella region, forehead, uh, temples, but you wanna be very careful when it comes to like right around.
Here. Mm-hmm. Um, but yeah, it's, it's very liquidy if it does get into the bloodstream, it's such a short half-life. Mm-hmm. Mm-hmm. Um, so luckily that is not a concern. Yeah. We did still aspirate when we did it because I'm just a psychopath. Yeah. But that's fine. Gab, gab actually did get on this side, we got blood return.
Yep. Yeah. So when people say you can't get a positive aspiration with a BD syringe, you can, and they're lying to you.
Oh, oh. I, I had both. I had one during a private training.
Yeah.
Yep. Under eye filler. Mm-hmm. Like, are you kidding? And and it was actually so cool to have it during a private training. Right.
Because it was like, oh, look at
it can
happen. You know? See, it
can happen. Yeah. Yeah.
And don't panic, you just pull out.
Mm-hmm. Some good life advice when in
doubt, pull out.
That's some life advice for everyone there. Oh my God. But I feel like that's like a major, a major question on, you know, from everybody is, is that a concern?
'cause with other things like sculpture, it, even with sculpture, it is a little bit of a, a concern.
Yeah.
Yeah,
sure. I,
that's, that's, that's a toss up that's in the air.
I, I mean, I think p if you got one of those little crystals in the particles, yeah. Mm-hmm. Sure. Mm-hmm. You know, but like, I don't know. I just, yeah.
I think it definitely, yeah. You don't want any, it could happen, it can happen to
me tomorrow.
Please knock on wood. That's why I'm knocking on wood right
now, but I have not seen it, at least personally in six years. Yeah. And I, yeah. I truly think it's, it was the person who taught me though, and I, I love her.
Suzanne Wilson. She's wonderful. Um, when I inject s Sculptra, I um, actually push as I'm, um, moving the syringe. So as I'm in. Injecting, can you help me?
Like not, um, as I'm injecting, as
I'm advancing the needle. Yeah. Under the skin also, I'm trying to get the
opposite of retrograde. Oh my God.
It's Friday folks.
It's Friday. Oh my God. Um, we're okay. We're fine. It's fine. But as I'm actually introducing the needle, needle, advancing it and advancing it under the skin, I'm actually pushing on the plunger and I'm injecting sculpture as so. Antegrade. Yeah, antegrade. Yeah. I was just
gonna say, yeah, antegrade.
I'm injecting antegrade actually.
Yeah. Yeah. So like the thought is, is if you're injecting antegrade, you're actually pushing away. Mm-hmm. Like any vessels. So I actually have less bruising mm-hmm. When that happens. So especially when you're trying to get that sculpture back into the hairline where maybe that TA is kind of hiding, like it really is helpful.
Mm-hmm. Um. Yeah. Nice. Mm-hmm. Oh my God. That was a struggle.
No, I'm laughing because this morning I was upstairs and I asked, I was texting Kevin just to see like, I'm like, can you make a bottle? But I said it the way that I would log it into the app. A baby bottle? Yeah. I said it, but like the way that I would log the feeding into the app, I literally texted, I'm like, can you.
Can you make 1145 feed?
Oh my God.
And I'm like, oh my God, I'm so sorry. I don't know why I typed that. I'm like, can you just, oh my gosh. Can you just make me a bottle?
I cannot.
Losing my mind.
Losing my mind.
Oh, we should probably mention Erica Wasim.
Oh, and of course, because, because they're the best, they're like the pioneers in this.
Yeah.
Yeah. And which is amazing. Just like, shout out their Patreon or whatever if people have questions. Olivia too, like
Olivia, I feel like Olivia was, and Erica, like those were the three that really like, I felt like, and, and if we're missing someone else, I'm sorry, but like, at least from on my end mm-hmm.
Those are the people that really were the pioneers for PDGF, for me. Mm-hmm. And, and highlighting it and what it can do. What? Maybe you wanna inject it and it's the best thing in the entire fricking world. If you're not injecting it, do it. Get on board. Yeah. Yeah. So
definitely I would, I would check out Olivia's page, Olivia Salman, we'll put that on here.
And then, um mm-hmm. Erica, Barry and Wassim. I don't. Know his last name, but they're on Patreon. Mm-hmm. They're on Patreon. They're on Instagram. Mm-hmm. They're all great resources. John's an incredible resource. He's been using this for months now too. Um, so if you have any further questions or wanna look up any other information, I know that Erica and I think have a webinar coming up with Dr.
Lynch X. Really?
Oh, that's awesome.
Yeah. So that'd be a good thing for people to look into too.
Yeah, so I think the takeaways for PDGF, you don't have to worry about a vascular occlusion, um, unless you are by this supra tr clear artery, right? Mm-hmm. Just 'cause the half life. Um, number two, you are, when you're injecting it, whether it's the under eyes, the smile lines, the accordion lines, the hair, you're reconstituting it with bacterial static saline.
Um, the recommended. Reconstitution for under eye smile lines, accordion lines is 1.5 ccs of bacterial static saline. Um, you can use either com, you can use needle, you can use cannula. I use the 25 gauge one and a half cannula, and it's always injecting it deep. Mm-hmm. Right into the tear chop. I sometimes also will save just a little bit and inject just that
lateral, lateral orbital rim
just to bones periosteum.
We did that on this eye here 'cause I was a little bit hollow on the one side. It's amazing. And I do think too, like we've, we've been saying like make sure you're injecting it deep. There is, yeah, there is. Use for it. A little bit more superficial too. There is, it's just that you wanna warn the patient that there is gonna be swelling and that angiogenesis, that redness and all of that.
Uh, but definitely where there's like etched lines or if someone's really hollow, like you might be able to do a couple little struts. Like there, there is some so nice. Some use of it superficially.
And this is coming from someone who injected it. I've gotten injected superficially. Mm. And I loved my results.
It, I just had had some said downtime. Yeah, you just had some angiogenesis, a little swelling for seven to 10 days, and then I was fine. Mm-hmm. So, yeah. Oh, the series of treatments really important. Oh, yes,
yes. That is a huge topic. Yes. Yes. So
comparative to PRP, you want to separate the treatments eight weeks apart instead of four to six weeks apart.
That's really important. Yeah. I feel like with PDGF because of how potent the growth factor is, you need less treatments than PP mm-hmm. Um, to get to your goal. Um, so obviously with PRP, you need like three to six sessions, uh, with PDGF. Minimum two, possibly three space out eight weeks apart maybe. Mm-hmm.
Just depends on the person and your hollowness and your goals.
Yeah, and I think like even someone like me who didn't really have anything intense in my under eye area, like I'm probably gonna be good with one. You know, there's definitely right. There's also, even though it's a growth factor, I feel like you can't overdo it.
So you just wanna make sure that you do wait that eight weeks and you see the result before you go adding more.
And the reason why. You don't want to bring them in prematurely and inject them maybe at the six week mark is because it's actually still working. That's how strong it is. Like I think it's working all the way up to that eight week mark.
If you inject them too prematurely, uh, before the eight weeks, they could just have more swelling and a little bit more into agenesis and more downtime for their second treatment.
Yeah. So really give
it the time to do what it needs to do. Yeah.
Mm-hmm. And I think too, like. For patients, I feel like it is a great selling point.
Like microneedling, we used to have to do three sessions with PRP. Like now you can potentially get away with one session with the PDGF, you know?
Mm-hmm.
So it is kind of exciting. Yeah.
Or you could do three, or
you could do three if you want. Exactly. I would do three. Exactly.
Yep. Yep.
I love it. Yes. Well, we'll probably wanna do another one of these episode in, in a two to three months, I feel like.
Mm-hmm. You know, as we continue to see this product be, evolve and change.
Yeah, I love it.
We'll keep you all posted, but feel free on Instagram and stuff. You can always ask us questions.
Yes. Leave any questions or comments about PDGF in the drop, like whether it's negative, positive, your experience with it.
Mm-hmm. We absolutely love it and thank you. We wanna hear it. And we do, and thank you so much for tuning into this week's episode of the Film and Pod.
We'll see you next time.
Love you guys.