Independent Insights, a Health Mart Podcast

Integrating Evidence-Based Functional Medicine Concepts into Pharmacy Care

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Interest in functional medicine and direct-to-consumer diagnostic testing continues to grow, shaping how many patients think about prevention, wellness, and chronic disease management. This course explores key concepts in functional medicine and examines how pharmacists can thoughtfully evaluate these approaches through an evidence-based lens. You will gain practical insight to support informed patient conversations while maintaining professional standards and scope-appropriate care.


HOST
Rachel Maynard, PharmD

GameChangers Podcast Host and Lead, Clinical & Partnership Education, CEimpact

GUEST
Josie Ross, Pharm D
PIC
Phillips Family Pharmacy and Compounding

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PRACTICE RESOURCE
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CPE INFORMATION
 Learning Objectives

Upon successful completion of this knowledge-based activity, participants should be able to:
1. Describe foundational principles of functional medicine and their relevance to evidence-based care in pharmacy.
2. Summarize factors pharmacists should consider when evaluating the evidence supporting functional medicine approaches.

Rachel Maynard and Josie Ross have no relevant financial relationships to disclose.

0.05 CEU/0.5 Hr
UAN: 0107-0000-26-308-H01-P
Initial release date: 8/17/2026
Expiration date: 8/17/2029
Additional CPE details can be found here.

Welcome And Why This Matters

SPEAKER_00

Hi, Health Bart Pharmacist. From your education partner CE Impact, this is Game Changers. I'm your host, Jen Moulton, and each week we have a conversation on a hot clinical topic that will keep you current in practice and position you as a resource for prescribers and patients. Thanks for listening in. Hi everyone.

SPEAKER_01

Welcome to the Game Changers Clinical Update podcast. I'm your host, Rachel Mayard, and I'm excited to dive into our discussion today about functional medicine. There's growing interest in functional medicine, and more patients are coming to us as pharmacists with questions about things like supplements, specialized testing, and root cause approaches to chronic disease. So today we're going to clear up the confusion about what functional medicine is, examine where the evidence is strongest, and clarify how to navigate these patient conversations using an evidence-based and patient-centered framework. And I'm so pleased to welcome our expert guest for this topic, Dr. Josie Phillips Ross. So welcome, Josie.

SPEAKER_02

Thank you.

SPEAKER_01

Great to have you. Very happy to have your expertise here today. And to help our listeners learn a little bit about you, maybe you could share a little bit about your background and your current role and why you're passionate about this topic.

SPEAKER_02

Sure. I first opened a retail pharmacy about 14 years ago in right outside of Kansas City, Missouri. And first we kind of started with just the general delivery and patient-centered approach for having a retail pharmacy. I started getting a lot of questions about how I can help patients in different areas of their life. And it really made me curious to start my own research on or go down the pathway of learning about functional medicine. So that's kind of how I started. It was patient-centered. And a lot of it came back to bioidentical hormones and specific supplements that they asked me about, or testing is more in the last 10 years. But the questions from the patients is what got me interested in going down the pathway of functional medicine. So that was almost 10 years ago now. I completed an A4M advanced endocrinology fellowship, as well as got my A4M practitioner license and completed an IFM with have a practitioner license there. And so now we run a compounding pharmacy, a functional medicine consulting business, and then a retail pharmacy. So that's kind of how I got started. It was it was based on patients asking me for help. And so now that's what I do full time.

SPEAKER_01

Yeah. Well, and one of my questions was going to be thank you so much, Josie, for that background and also for spending the time with us today. I know you got you're super busy, got a busy practice. Um, but that was going to be one of my questions is why do you think even in the last 10 years? So this started early for you, but I think even more recently, functional medicine has gotten a lot of attention, a lot of buzz. Sort of this term I shared with you, I'm not super familiar with it. So I think helping us understand what functional medicine is and how it's different or similar to sort of that traditional conventional medicine, how would you describe functional medicine to a colleague?

What Functional Medicine Actually Means

SPEAKER_02

So when we're talking about functional medicine, we are talking about an individualized approach, right? So it begs the question: why? Why do you have diabetes? Why do you have hypertension? What kind of scenarios, lifestyle factors, environmental factors, genetic factors got you into these chronic disease states in the first place? So I think it truly goes back to the why of most chronic diseases and tries to peel back the layers to figuring out the root of these chronic diseases and how to fix the root. That's why we coined the term root cause medicine. Instead of putting you in the box of treatment-based, it's more of prevention and or looking for why you have these chronic disease states in the first place.

SPEAKER_01

Okay. So that's great clarification. And I think that focus on prevention versus treating after the fact is so important. And I think we can all agree with that. That is something we've all learned about in pharmacy school is the importance of prevention. But um, that sounds like the foundation of functional medicine versus the treatment after the fact. And again, as pharmacists, we're often thinking about the medications, the treatments, but reframing that and focusing more on prevention. That's a fair summary.

SPEAKER_02

Yeah. And I and I think in in when we're taught as pharmacists, right, we we get um all of the knowledge of the drugs and how they work and all of that, but very little about lifestyle factors and environmental factors, genetic factors, like those types of things that play a huge role in these diseases. So peeling back why functional medicine to me is figuring out the why.

SPEAKER_01

Okay. Are there any other sort of um you mentioned the root cause, but also that personalized care and really focusing on the patient. So the why for that patient, right? And so digging a little deeper into all of those specific factors that might have come up for them and that's leading to where they are now. Um, and I think that really ties in nicely with what you shared earlier about patients coming to you asking these questions, and maybe you were encouraging them to ask that why and to dig a little deeper into why they got to where they are now. So it makes me wonder why do you think patients now, more so than ever, are interested in functional medicine, hearing about functional medicine, wanting to pursue people with expertise in this area?

SPEAKER_02

Yeah, great question. I think that obviously social media has brought a lot to the forefront and asking more questions and being your own patient advocate. I think that that's so important. I think our healthcare system is overburdened everywhere you look, right? Um, our chronic disease is about 60% of Americans now. And there's many factors to that reasoning, but we have to figure out another pathway. We are overburdened with chronic disease. So we have to figure out the whys at this point. And I think the patient population either isn't getting answers to their specific questions and they're looking elsewhere, or trying to be their own patient advocate to figure it out for themselves. We're seeing a lot of that now.

SPEAKER_01

Mm-hmm. And I agree. I mean, information is also more widely accessible too, not only on social media, but AI and everywhere. So, yes, they are accessing information that they didn't have 10 years ago and leading to some of these questions for themselves and looking for expert advice and coming to us as pharmacists, I think, oftentimes for that, which is, or or if they're not, maybe they should be, and we should be serving as that expert. So you talked a little bit about your your training here and and in this area. So for people listening, I mean, what sort of additional education resources, where where can we be thinking about getting some additional information if you're new to this sort of space?

SPEAKER_02

Yeah, I think I think starting with the questions of why, right? Um, if if you're a pharmacist and you're questioning, okay, why is this patient on 16 minutes? They're coming to me asking about all these side effects. Like, what can I do in order to help them become healthier in general? Like we all went to pharmacy school to help patients, correct? Not give them more disease burden and more drugs, right? So I think peeling back that layer of the why. And then if you're curious on functional medicine, there's a lot of different programs out there to learn. The ones that I was trained in, obviously, but there's also tons of publications now, many resources, many books, many MDs that are practicing this way too. So coming out with different publications and books as well. There's lots of places to start when you're looking into functional medicine now, as opposed to 10 years ago when I started.

SPEAKER_01

Right, right, right. And and that's where I do, I do think it's this term that's getting a lot of buzz. And so thank you for helping to clarify that and also sharing some of those um, you know, concepts related specifically to functional medicine and where that fits in. So, in terms of that overlap um with conventional medicine, where would you say are the biggest areas of overlap? Again, we we think about prevention in in traditional medicine too, but uh would it be sort of lifestyle sorts of modifications that we should be thinking about? Where are those sort of common areas of common ground?

Where It Fits With Conventional Care

SPEAKER_02

Yeah, so I always say that you're gonna need both functional medicine and conventional medicine, right? For for treatment basis. I would never take a patient that has diabetes off of their diabetic medications, right? We would teach them, you know, through different programs of CGM or testing, or we would teach them what their body needs in order to decrease on those, but I would never start with like you need to go full functional medicine or full conventional medicine. I think it has to be a bridge of both. But the where we both find common ground is the lifestyle factors. Functional medicine is more based on those, and conventional medicine brushes the top of that, right? What we're taught on our one nutrition class, or you know what I mean, the small lifestyle factors that we get in diabetic education. So it's more about teaching and learning, and on that front for the lifestyle, environmental, all of those things, but they they both need to be used together, is what the people do not have to go full force one or the other.

SPEAKER_01

That's a great uh point to clarify because even if you if you have a patient who is interested in functional medicine, seeing a functional medicine provider, it doesn't mean they're not coming to your pharmacy for other for you know their prescription medicine.

SPEAKER_02

You know, sinusitis and stuff like that. Right. So yeah, you definitely need both.

SPEAKER_01

Okay. Okay, that's good clarification. So the the fact that this is still sort of a growing area, I think, begs the question of well, what is the evidence to support the various area, you know, uh interventions that might be done in functional medicine. And maybe you can share a little bit about uh what sorts of interventions are maybe thought of commonly with functional medicine and the evidence to support those and how that may vary based on the specific approach you're talking about.

Evidence For Diet Exercise Supplements

SPEAKER_02

Right. So there's there are a lot of things with strong evidence uh in the lifestyle category. Obviously, diet being one of those, Mediterranean diet has tons and tons and tons of studies, lots of evidence to support that type of eating and anti-inflammatory lifestyle. So diet is one area. Um exercise also has a ton of studies and support and evidence, as well as strength training. And then there are some studies with uh supplements, specifically like omegas, vitamin D's, creatine now is a new one that's getting a lot of support in studies. There, there's definitely a lot of evidence for those types of things.

SPEAKER_01

So, how do you go about assessing, like say, say you have a patient who hears about a particular supplement, for example? How do you go about assessing whether that is something that what what level of evidence there is to support that particular supplement and how that fits in with the patient specifically? I know that's a pretty big question. So maybe, maybe when you're thinking about a supplement, for example, or any other intervention, how do you go about assessing the level of evidence to support that intervention? Okay, good question.

SPEAKER_02

Um because that needs to kind of start out with supplements don't have the billion-dollar industry that other drugs do. So the studies are limited based on support from other groups, but I typically take it patient-by-patient basis. So my job is to assess the full patient from their history to their symptoms to their family history. And I kind of match and labs, we we evaluate tons of labs. So I work through the knowledge that I have gotten from the different education places that I've gotten. Um they provide tons of resources and studies for everything in particular that they're teaching, obviously. So that's a great resource to have. Um, but this is very patient-specific. So I think that that's important to learn. And when you're a pharmacist and you're at the counter and somebody's asking you about a supplement, just right off, you know, you're doing a thousand things. There's just a few that obviously you need to be aware of, you know, for the anti-inflammatory purposes or the drug depletions that I know we'll talk about. Um, there's not a lot of time for a pharmacist to truly dive in to the evidence supporting supplements with everything on their plate. It's it's that's why this whole other uh career path has been born for people begging the question and wanting more answers and wanting more time. So my consultations are typically 30 minutes to an hour per session. So you get that time and individualized treatment protocols, lifestyle factors, all of that.

SPEAKER_01

And in those sessions, I'm uh thinking you probably do like a medication review to be able and and including supplements, all all basically again, that holistic approach, right? Yes, absolutely. Yeah, yeah. So uh you mentioned a few examples like the Mediterranean diet and um omega-3s or and then some other, and uh like you say, there's thousands of supplements out there. So it's really hard to keep up with all of them and all the emerging evidence with them. And so again, with any specific intervention, I think we were chatting a little bit earlier before the start of the podcast about how there's a sort of spectrum of evidence with anything in medicine and including functional medicine from randomized controlled trials, which are often considered the gold standard, all the way to sort of expert opinion or anecdotal evidence that from a patient as you're working with a patient. So, you know, there's that whole spectrum. And I think that's where it gets a little difficult with thinking about evidence-based approaches because sometimes you are tailoring to the patient and and what works for them. And, you know, that that's very specific. Maybe you could speak a little bit more about that or some some experiences you've had.

SPEAKER_02

Well, and truly, I was I was talking to you too. It's it's all about like trial and error in this field, too. Um, because all of my training, I've been in this world for eight to ten years. And so obviously, I know what works now, I know what doesn't work, I know what patients respond to, I know what they don't respond to, I know what testing to do, I know what testing not to do. So it's been a labor of love per se for a long time. So just diving in feet first um obviously is hard to do in this realm without the education piece. That kind of gives you the forefront and the background uh to start with for functional medicine. But um, yeah, it's a it's a tricky field to navigate, I would say.

SPEAKER_01

Yeah. Yeah. Well, okay, let's because that's tricky, and we're talking at very high level here. And there's, you know, I keep saying interventions, but what are we specifically talking about? Um, so one example that I think is helpful to think about is with drug-induced nutrient deficiencies or depletions. And

Drug-Induced Nutrient Depletions Explained

SPEAKER_01

that's something that many pharmacists may know about, regardless of their background, simply because we know there are certain prescription medications that lead to some of these deficiencies. So maybe you can speak to a few what that means in a bit more detail than what I just said, and also some examples that often come to mind and how you manage those when you see patients on these medications.

SPEAKER_02

Yeah. So I would recommend to all pharmacists to have a chart to print off for them to be able to recognize on a quick manner what is being depleted. But also, we also talk about these drugs giving the deficiencies and causing them, but we don't consider what's happening in the background too. So, what if like metformin decreases B12? So, what is B12 used in? What is it a cofactor of all of these support systems? And we talk about it and kind of throw it in the air, like, oh, you need B12, but like actually go back and why do you need B12 in your body? Like, what is it used for? What processes is it needed for? Same thing with like birth controls. Birth controls are a big one that deplete many nutrients, and all of those nutrients are used for specific things in your body. So not only is it a nutrient deficiency, but it might be causing a lot of symptoms in your patient that you might be completely unaware with. You know, fatigue being one of those, um, restless leg syndrome being one of those. Like there's tons of things, uh, brain fog, skin type reactions. There's tons of things that the symptoms could show up because of these nutrition deficient nutrient deficiencies that we're not even considering. We're just throwing around like, oh, this drug can cause that. And maybe mentioning it to a patient, but not considering the background of what it could be causing for that patient.

SPEAKER_01

And I think that goes back to your earlier point why of why why are you having those symptoms and ruling in medications as one potential cause before you can rule them out and sort of thinking through that whole perspective and possible consideration on why that might be having those symptoms or that problem.

SPEAKER_02

And one area that I always hone in on is detoxification through the liver process, right? There's three processes of detoxification. Most of those need tons and tons of nutrients to help make things soluble and get out. And a lot of our food is stripped of it. And now we're getting drugs that are stripping our body of those nutrients. And so it's like a twofold approach. Like if we can't process things out properly, now we're having all these symptoms on top of that. But we don't even consider that when we're talking about these drugs just causing depletions, you know what I mean? So getting a chart to let you know, like, and then putting the why behind it. Like if a patient is deficient in iron or B12 or vitamin C, what is that causing? And what's that going to show up? Like if a patient comes to you and like, I'm so fatigued, and you look at their patient profile, like, oh, you're on metformin. Like, this is what we can do to hand-in-hand approach. That is like the number one place for a pharmacist to start. But you have to question the why. You can't just put the horse before, right? You you have to question the why and what is it causing in the body in order to actually put the elements together with the patient and the symptoms. I think that that's the most important part because we do throw around that a lot as a pharmacist. And even in the hospital, it's it's gaining some traction, right? We're giving OTCs in the hospital a little bit more, but pharmacists aren't considering what's that doing or symptoms that's exhibiting in a patient to put those together. So I think that that's that's more important to go back to the why too.

SPEAKER_01

Well, and I I like how you called out that this is a very narrow consideration. The why helps make it broader, but also thinking about okay, even if this person is potentially taking a medic medication that might deplete uh B12 with metformin, for example, there's also the dietary considerations. It goes back to the nutrition and your total lifestyle approach. Yeah, yeah. And so it really does tie back to sort of that preventive and holistic concept and ensuring, okay, we're not just necessarily giving you a B12 because you're on metformin, it's because you we also have to think about what is your diet like otherwise, and and how is that contributing to your overall health?

SPEAKER_02

Yeah, yeah, there's huge misconceptions with diet as well in our health care today. I would say I feel like what, especially when I was sitting in functional medicine school, I was like, this needs to be public knowledge. Like this needs to go out to everybody, everybody needs to learn the nutrition piece aspect behind all of this. We would all much be in a much better place if we did, and maybe not need as many of these interventions. But um that nutrition plays a huge role, right? With how you feel. And and there's a lot of misconceptions too with symptoms nowadays, like, oh, you're getting older, you're probably gonna be more fatigued, or you know, these types of hormonal issues. It's normal to be constipated, or it's normal to have gut issues or or feel bloated, like those things are are normal, but they're really not. And so honing into the why that's happening behind that is really important. And knowing that these things might be common, but they're not normal.

SPEAKER_01

And yeah, going back to that idea of the patient advocate and and wanting to not just saying, okay, I guess I I have this symptom and I'm gonna live with this for the rest of my life, but digging a little deeper to find out what might be able to help with that. Yeah, absolutely. And so when thinking about maybe those conversations with patients and how to help direct them to what's going to most benefit them, where do you start in that sort of triage process? Like what are what are some the key things that you're thinking about when a patient is coming to you, maybe with a symptom? And how do you identify what might be the cause?

SPEAKER_02

Yeah. So I I look at all of my patients like a puzzle and I'm putting the pieces together. And I've done that from the start. I love puzzles, I love logic problems. Like that's what I love to do. So it kind of fits in right where with what I love. But I usually use the cannabis of what we have, lab-base-wise, symptom-based-wise, history-based wise, just even like the small factors of like heat sensitivity or chemical sensitivity, like those things all matter when you're talking about symptoms and causes. So I like to put the why in all of those categories and go kind of brush back. Go through we go through diet, we go through lifestyle, we go through obviously medications, diagnoses, OTCs, um, family history. It's really a deep dive into why and how they're feeling right now. A lot of my patients are hormone patients. We do a lot of bioidentical hormones. Um, and so a lot of those factors come into play, especially when we're talking about metabolizing hormones out. Are you doing things that are hurting or helping that process? Those are those are key things to look for and they're important to me as far as doing no harm, extra harm to the patient and making them feel better, obviously. Because you're you're gonna gain patients just by them feeling better, truthfully. It doesn't even have to be a lab number. It's just like this pharmacist made a difference in my life because I feel this much better on these specific symptoms.

SPEAKER_01

Absolutely. Yeah. I think we can all relate to that, right? Where we've had patients that we've made a positive difference. And if you can do it with something, I say S. simple as a lifestyle change, but as um maybe uh benign. I I don't know what the word is, but something that's simple and just something maybe they hadn't thought of in the past, you know, that that can make a huge difference. Yeah, I agree. So when thinking about you mentioned sort of the I think you alluded to the safety considerations.

Supplement Quality Red Flags

SPEAKER_01

And so are there any sort of red flags that you would want a patient asking about some particular product or process?

SPEAKER_02

Any any safety considerations that people who aren't as familiar with functional medicine should be aware of and helping patients steer clear of so first thing that I consider especially on the supplement base is professional grade, ones that have certificate of analyst of exactly what's in them. It is a huge market like you said and regulations are some are there but there are a lot that are not. And not the same as prescription drugs. Again like not regulated like that regulated. Yeah they're technically regulated as food right um and there's not a lot of regulation in that field either but that's to say I usually use professional grade because I can have a certificate certificate of analyst to know exactly what's in them. That's super important. Quality is super important when you're when you're talking about these something as simple as omega threes if we go back to that there is a specific point where those omegas can get rancid and so if you're taking a rancid omega three it's actually causing more inflammation and you're the reason you're taking it is to decrease inflammation. And so obviously that's not a regulated field for the rancidity of omegas. So having something in place or looking at places that do that study is important for us. And that's just like one super specific example but I think having that know how in the professional grade is really important when I'm recommending or even storing those on the shelf.

SPEAKER_01

That's important for me. Absolutely and I think I mean the thing I learned about is looking so maybe not everyone has access to the COAs like you're talking about if it's something you're ordering specifically but for a person looking on a shelf even like the USP verification or I think there are some other certifications that are available that at least is like another check to make sure that they have what they say they have in the box at least.

SPEAKER_02

Agree agree and that should be on the bottle either professional grade will be listed almost every single professional grade is going to have a certificate of analyst so you can actually call the bottle and say can I see your certificate of analyst they should be able to send it we send ours um pretty quick. And so just having that knowledge if you're housing or storing them in your pharmacy that's important to know the regulating bodies how to look for those C of A's if a patient were to ever ask you because I'm sure patients are listening to this and they might start asking great point.

SPEAKER_01

Yeah absolutely and I mean I think too um because it's not just in pharmacies right people are are getting supplements online from friends, neighbors, you know, who knows and so as you said it's it's sometimes hard to tell but there are some steps we can take to at least confirm the quality is there. Because there there have been cases where supplements have been because as we said before they're not um tested for safety and advocacy the same way as prescription drugs. But once they're on the market FDA can pull them or you know cause with recall if they are found to have contaminants or found to cause harm or these sorts of things but it's after the fact. And so we don't want people to be taking something potentially risky in terms of do no harm, do no harm. Right. Do no

Interactions And Full Patient Profiles

SPEAKER_01

harm yep we all sign out of and then I guess along those lines too in terms of safety so thinking about um in in how do you approach a patient with the considerations of potential interactions with maybe other prescription medicines they're taking or other supplements they're taking or dosing what kinds of thought processes are you using when evaluating that?

SPEAKER_02

Yeah so having the full patient profile because a lot of times they'll think like oh I got these supplements OTC and they're not even considering an interaction between their medications and asking those specific questions are you taking any over the counter medications? Are you taking supplements? Because then they will identify that oh yeah I am taking this vitamin D and K2 and give you those kinds of information that is a lot of times not in the pharmacy profiles right in the pharmacies we don't have access to what they're taking outside of what we are giving them. So having that kind of data is important. Asking those kind of questions to patients is important. Disease state and symptoms is also important if it's a time limiting factor. So if you have a pharmacist that is doing something in the functional medicine realm and kind of guiding them for more help if they're asking for it so they can get all of the details.

SPEAKER_01

Yeah I think again for for any pharmacist regardless of practice setting those are just good reminders to be aware of and again sort of principles we've often learned in pharmacy school but good reminders regardless. Yeah I agree.

SPEAKER_02

Are

Gut Health And Whole-Body Thinking

SPEAKER_02

there any other areas of functional medicine that you think uh listeners should know about as sort of uh emerging or potentially those that are you know have a strong evidence base that we haven't talked about yet so gut health is a huge one right now and I think that in our conventional care model they're identifying inflammation and not identifying causes of inflammation and so I feel like that's a big area for functional medicine with a lot of emergent emerging um details and studies probiotics are becoming widely used and accepted and studied and so that I feel like is a going to be a huge topic obviously coming up and that also plays a role with how we're processing out our drugs and our as well as supplements but also like mental health obviously everything's connected and I think that that's another difference in conventional medicine is is we go to specialties in order to like endocrinology specialty gastro specialty in functional medicine I look at this as related to this as related to this as a whole body system. So that that could be a a difference as well.

SPEAKER_01

Mm-hmm yeah I mean I think and again I think we are getting a better understanding of how that all interacts and you know we are one person so it makes sense that this is all interconnected in some way. But and again goes back to your point about the the why and what might be causing this symptom is it is it just something that that's passing or is it something that's related to a more chronic potentially issue?

SPEAKER_02

Agree.

SPEAKER_01

Yeah yeah so what what else would you advise pharmacists about that to think about if they're supporting patients with functional medicine just as a sort of a broad broad approach, having those conversations patients are asking what what like key takeaways would you recommend that pharmacists be thinking about or be aware of before those questions get asked?

SPEAKER_02

Yeah I mean going back to to the the why like for our own information to help patients navigate this field because it is going to be talked about a lot more in the future and you are going to start getting questions no matter if you work in a hospital or community setting you're gonna get a lot more questions about functional medicine or even homeopathic therapies, supplements you're gonna be getting a lot more questions because there's a lot more information out there. Like you said it's everywhere. Information is at patients' tips of their fingers. So asking the why, right? So even if you have a patient and that you have no idea they come to you for fatigue or have a question about migraines or brain fog or something like that. And asking the why like doing a little bit of research on your own is going to be helpful for you to navigate those patients moving forward or identifying similarities in other patients um especially with nutrient depletions and correlating those and being like oh I remember that this can cause this and this patient might have the same thing going on. Obviously they are all bioindividual but we do have some similarities and overlap with that when it goes back to especially nutrient depletions.

SPEAKER_01

Mm-hmm and maybe just quickly you can give we gave metformin as the example are there other sort of three to five that come top of mind to you?

SPEAKER_02

PPIs are a huge one or any type of acid reducer is a huge one. Birth control is a huge one a lot of seizure medications have a lot of nutrient depletions as well as blood pressure medications they all have um some major and it's not commonly one like metformin probably more than one but most of the studies are on the B12 for metformin. They just haven't done enough studies to see what else it depletes because obviously that takes a lot of time and sure yeah yeah clinical knowledge.

SPEAKER_01

Well and interestingly um I saw that there was an FDA warning just recently or alert about vitamin B6 deficiency and associated seizures for drugs containing carbidopolividopa. So just another example of how this is continuing to be studied is going to continue to come up and another possible thing to have on your radar when you're seeing patients on carbidopolidopa as just one example. Also to the the other thing that comes to mind is people with a particular diet so like vegetarian or vegan diets, that's it's not just medications too it's also your dietary and again tying that back to the nutrition aspect as well. So thinking about that that holistic approach and full patient approach.

SPEAKER_02

This has been fascinating for me and I think going back to the why yeah yeah for like these things that's a co-factor in many systems throughout the body and so what that can cause and what that can show up as symptom wise in a patient is important to notate before you know seeing the patient's roll in with the sufficiency.

SPEAKER_01

Right. And I I think um the get the sense I'm getting is that in your education you got a lot of that additional background in terms that we maybe didn't get in pharmacy school the rest of us in terms of sort of that physiological how it all ties together physiologically and and how that can impact clinical symptoms even from this sort of mechanistic approach. Absolutely yeah so yeah like I say this was great discussion great overview of what to be thinking about with functional medicine. I think we got some uh practical points in there and just thinking about sort of that uh person-centered approach that root cause consideration that why those were the things that came through to me and also the considerations around safety and prioritizing that um and understanding that we have this varying level of evidence for certain interventions but you know that's that's okay we just have to work with the patient and and work

The Game Changer Ask Why

SPEAKER_01

through that.

SPEAKER_02

So Josie, we always wrap up with the game changer and so what would you say is the game changer around this topic that you'd want our listeners to walk away with I would say we'll stay on the theme of questioning why I figured that yeah I would say I would say because honestly one of my first um questioning why is I had a I had a patient come to me he was a business owner in his 50s very vibrant and then I saw the rapid decline in his health over like eight years and I started asking why like why is this happening? Why is early onset dementia is it hereditary is there some nutrients that are missing are like I started questioning why in my own head and that's what kind of led me to dig deeper is those specific patients that led me to the why. So I think that as pharmacists we get into maybe a mundane routine of doing the same types of things and if you look out more broad spectrum and say okay I need to start asking why like why is that patient asking for folate? Why is there slow? What is that causing the body? Like simple things that you can start putting together just for your own knowledge and to help your patients in any setting that you're in any pharmacist setting.

SPEAKER_01

Absolutely I love that that's a great wrap up and again I think we are pharmacists so traditionally we think about medications but it is much broader than that when we're thinking about taking care of the whole patient.

SPEAKER_02

Yeah and then even in the next 10 years it's going to be a changing ever changing field.

SPEAKER_01

Yes yes absolutely so we'll have to have you back on as things continue to evolve.

SPEAKER_00

They will they will for sure Josie thank you so much for your time this was great and uh really appreciate your perspective and expertise here awesome thank you and that's it for this week be sure to log in to Healthmart University to claim your CE credit for this episode. As always have a great week and keep learning we'll talk to you next week.